Patients with early Lyme disease appeared to be depressed when evaluated with the Beck Depression Inventory (BDI-II) tool, according to a study by Wormser and colleagues, published in the American Journal of Medicine.  But after antibiotic treatment, the patients’ BDI-II scores returned to normal, leading the authors to conclude that these patients, in fact, did not suffer from depression.
There have been multiple reports documenting cardiac manifestations of Lyme disease, including Lyme carditis, Lyme endocarditis and atrioventricular block. But valve problems caused by B. burgdorferi are rare. In a recent article “Lyme Disease-An Unusual Cause of a Mitral Valve Endocarditis,” Fatima and colleagues describe what they believe to be the “first documented case of mitral valve endocarditis [caused] by B. burgdorferi in North America.” 
The incidence of an erythema migrans (EM) rash, a definitive sign of Lyme disease, has been touted by Shapiro and Wormser as occurring in at least 90% of patients. Their claim is published in a recent letter to the editor in JAMA.  So, how did they reach this conclusion? The answer lies in the two studies they cite. [2,3]
The medical literature typically describes Lyme carditis cases occurring in the Northeastern USA. But a recent article in the Journal of Electrocardiology features the case of a 23-year-old woman with Lyme carditis from the Northeast region of Mexico.
There have been limited studies investigating the impact of age on the clinical course and treatment outcome for Lyme disease. Now, a European study by Borsic and colleagues examines whether age is associated with treatment response.
There are a growing number of measures promoted to prevent Lyme disease. Yet, the number of cases continues to grow. So, how effective are these prevention methods? To answer that question, Richardson and colleagues reviewed the literature on such recommendations. In their assessment, the authors used a modified Cochrane Risk of Bias tool.
This past year, Lyme Disease Science blogs have covered a wide range of topics on tick-borne illnesses with subjects ranging from atypical case presentations to new, emerging diseases to innovative tick tracking methods.
Doctors typically use the one microbe, one disease Germ Theory when trying to identify diseases in their patients. Lyme disease initially fit this theory after Dr. Willy Burgdorfer discovered that a spirochete (later named Borrelia burgdorferi) was the bacterial pathogen causing Lyme disease.
Researchers in Canada describe the same struggles with under-detection of Lyme disease that are seen in the United States. “Public health information is signiﬁcantly under-detecting and under-reporting human Lyme cases across Canada,” writes Lloyd and Hawkins in the journal Healthcare. 
Studies have shown that as many as 34% to 62% of Lyme disease patients remain ill years after treatment. [1,2] Wormser and colleagues have proposed using the term post-treatment Lyme disease syndrome (PTLDS) for patients who remain ill after 3 weeks of antibiotics.