Borrelia spirochete are masters at evading immune system

If the Borrelia spirochete were actively dividing and spreading during infection, it would be easier to detect Lyme disease and possibly diagnose it earlier, says Embers and colleagues. [1] “Bacterial pathogens are well known to cause tissue damage by colonization, induction of intense inflammation, invasion of host cells, and production of toxins.”

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Case report: Persistent pain and fatigue after treatment for Lyme disease

“A previously healthy 48-year-old woman living in rural Maryland presented in early June with a 2-week history of neck pain, fatigue, anorexia, nausea, and intermittent fevers and chills,” states Novak from the Division of Rheumatology at Johns Hopkins University School of Medicine.

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Case review: 80-year-old with Lyme encephalopathy instead of dementia

“An 80-year-old patient was admitted to the hospital after a fall, and subsequently developed an acute confused state requiring transfer to a neuropsychiatric unit,” writes Karrasch and colleagues in the journal Ticks and Tick-borne Diseases. [1]

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Year in Review: All Things Lyme: Top 10 blogs for 2017

by Daniel J. Cameron, MD, MPH Following is a list of the most popular All Things Lyme blogs for 2017. Click on the headline to read the complete article. 1) 12-year-old boy suffers cardiac arrest due to Lyme disease In the February 2017 issue of HeartRhythm Case Reports, doctors describe what they believe is the first case of a Lyme disease patient presenting as fulminant myocarditis and cardiac arrest. “The patient is a 12-year-old previously healthy boy with a recent history of participation in an outdoor camp for 2–3 weeks who began to gasp for air while ...

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40 years after first case, Lyme disease still a burden for Connecticut

“The town of Lyme in Connecticut was the first spot that LD [Lyme disease] was recognized in the U.S.,” writes Mollalo and colleagues in the journal Geospatial Health. [1] In 1977, Steere et al. described the initial cluster of cases in children. Today, 40 years later, Lyme disease continues to be a burden for Connecticut.

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Case report: 46-year-old Canadian man with Bell’s palsy

The number of reported cases of Lyme disease in Canada has jumped dramatically ─ with a 6-fold increase between 2009 and 2015, according to the most recent statistics. Most cases are believed to occur in Ontario, Quebec, and Nova Scotia. Given the alarming rise, knowing which symptoms to watch for to accurately diagnose the disease has never been more important.

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How to test for Lyme disease using a tick

It can be difficult to prove Lyme disease with serologic tests. So, doctors took an unusual approach with the first in-human study to identify the infection with Xenodiagnosis. Using this methodology, uninfected larval ticks fed on 23 study participants. Two of them tested positive for B. burgdorferi, the causative agent of Lyme disease. [1]

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CDC advises doctors to consider Lyme disease in emerging states

The Centers for Disease Control and Prevention (CDC) is advising doctors to consider Lyme disease in states where the condition is emerging, according to the authors of a recently published article in Morbidity and Mortality Weekly Report (MMWR).

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MS and Lyme disease patients call for more participation in clinical trials

Patient advocates have long been involved in lobbying for patient rights and providing outreach and educational awareness of their disease. In the past, “Trials were conducted on their behalf, often without incorporating the needs and views of the participants, and rarely were the results of the trials shared with the study participants,” states Smith in an article published in the Multiple Sclerosis Journal. [1] But times are changing and patients' voices have grown louder as they demand more involvement in research and clinical trials.

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Depression common in Lyme disease patients

There is still reservation among some in the medical community as to whether mood disorders, such as depression, are, in fact, associated with Lyme disease. The authors of a study published in Clinical Infectious Diseases explore the possible connection.

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