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Fatigue can be overlooked as a “sign” of Lyme disease

There are several objective signs of early Lyme disease, including Bell's palsy, synovitis of the knee, the presence of an erythema migrans (EM) rash, uveitis, bursitis of the hip and shoulders, and sacroilitis. However, severe fatigue has also been described as a sign of early Lyme disease (LD).