How the incidence of an EM rash can be inflated

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Both studies, published in 1996 and 1998, required that the participants meet the Centers for Disease Control and Prevention’s (CDC) surveillance case definition for Lyme disease. This definition requires that the erythema migrans rash be at least 2 inches in diameter. But the incidence of an EM rash is lower in studies that are all-inclusive […]

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