Persistent Lyme infection or inflammatory immune response?

Persistent antigen Lyme arthritis has gained attention following research suggesting that Borrelia burgdorferi peptidoglycan fragments (PG(Bb)) may drive inflammation even after antibiotic treatment. According to Jutras and colleagues, PG(Bb) fragments likely “contribute to inflammation during infection and in cases of post-infectious Lyme arthritis.” In a mouse model, the authors found that PG(Bb) alone was sufficient […]

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