biofilm-lyme-disease

Round bodies, blebs and biofilms in Lyme disease

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In an effort to better understand their significance, Corak and colleagues “grew B. burgdorferi spirochete, round body, bleb, and biofilm-dominated cultures and recovered their transcriptomes by RNAseq profiling.” Their non-spirochete morphotypes were induced by simple changes in growth conditions. The authors described three pleomorphic forms as follows: “Spherical B. burgdorferi cells with intact and flexible […]

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