The electrical jolts started without warning. Every few minutes, Lisa felt a sudden shock run through her head, like a live wire had touched her brain. The sensation would shoot down her spine, leaving her briefly disoriented, as if her nervous system had misfired. “It feels like my brain is short-circuiting,” she told her doctor. Instead of understanding, she was met with a puzzled look and a suggestion to try stress management.

She wasn’t imagining it. She wasn’t anxious. She was experiencing brain zaps and internal vibrations in Lyme disease — symptoms many patients describe vividly, even though they remain widely misunderstood.

You’re Not Losing Your Mind

If you’ve ever felt a sudden jolt inside your head, a flash of electrical energy behind your eyes, or a deep internal humming that no one else can see or feel, you’re not alone. Patients describe these sensations with remarkable clarity, and these descriptions align with recognized neurologic patterns.

These symptoms emerge when the nervous system becomes inflamed, overstimulated, or destabilized — all common in Lyme disease and other post-infectious syndromes. The sensations may be invisible externally, but they are grounded in physiology, not psychology.

What Brain Zaps and Internal Vibrations Feel Like

Brain zaps often feel like sudden, electric shock–like jolts inside the head. Some describe a bright internal flash, a momentary “reboot” sensation, or a sharp pulse that radiates into the neck or spine. These sensations can be startling and may be followed by brief dizziness or a sense that the brain’s internal circuitry has misfired.

Internal vibrations feel more like a deep buzzing or internal shaking, as if the body is trembling on the inside. Some describe a constant humming or vibrating sensation, especially at night or when the body is still. Both zaps and vibrations often intensify during Lyme flares, periods of stress, hormonal shifts, weather changes, or transitions between sleep and wakefulness.

The Science Behind These Sensations

Although these experiences can feel frightening, the mechanisms behind them are well described in neurology.

1. Central Sensitization

Following infection or inflammation, the brain and spinal cord can become hyper-responsive. This state, known as central sensitization, makes ordinary internal signals feel amplified or unstable, which can manifest as sudden electrical jolts or flashes.

2. Autonomic Nervous System (ANS) Dysfunction

Lyme disease often affects the autonomic nervous system. When the sympathetic “fight-or-flight” system remains overactive, patients may feel internal shaking, buzzing, or trembling even when no visible movement is happening.

3. Neuroinflammation

Inflammation caused by Borrelia burgdorferi can irritate sensory pathways and alter nerve-firing thresholds. When these pathways become unstable, the brain may generate shock-like or buzzing sensations in response to internal changes that would normally go unnoticed.

4. Sleep–Wake Transition Instability

Many people notice these sensations most strongly when falling asleep or waking up. These transitional periods involve natural shifts in brain electrical activity, which can feel abrupt or jarring when the nervous system is sensitized or inflamed.

What the Research Shows

Although no studies have examined the term “brain zaps” in Lyme disease, the medical literature offers meaningful parallels that help explain these sensations.

Brain Zaps

In published research, the term appears mainly in studies of antidepressant withdrawal. Patients in these studies describe sudden electrical jolts, internal flashes, and brief shock-like sensations — confirming that the experience itself is real, even if the specific context differs.

Internal Vibrations

Internal vibrations, sometimes called internal tremors, have been documented in post-infectious conditions such as Long COVID. Patients report deep internal shaking or buzzing that is invisible externally. Researchers link these sensations to dysautonomia, POTS, and small-fiber neuropathy — processes also seen in many Lyme patients.

Relevance to Lyme

Although Lyme studies may not use the term “brain zaps,” they describe neuropathic firing, sensory hypersensitivity, small-fiber neuropathy, and autonomic dysfunction. These physiologic mechanisms can easily produce the same electrical jolts, buzzing, and vibration sensations reported in other post-infectious conditions.

In short: the label may differ, but the neurology behind the sensations is the same.

“Brain zaps and internal vibrations are physiologic nervous-system symptoms — not anxiety.”

You Deserve Medical Recognition

Patients should never have to convince anyone that these sensations exist. Brain zaps and internal vibrations are neurologic manifestations of infection and inflammation. Even when MRI scans or nerve studies appear normal, the nervous system itself may be irritated, disrupted, or inflamed — changes that routine tests do not always capture.

Understanding these mechanisms helps both patients and clinicians approach these symptoms with clarity and validation rather than confusion or dismissal.

Your Experience Matters

Have you experienced nighttime brain zaps?
Did internal vibrations begin after a tick bite or flare?

Share your story below — your perspective may help someone else finally understand their own symptoms.

References and links

1. Brain Zaps Research
   Papp A., Onton J. Brain Zaps: An Underappreciated Symptom of Antidepressant Discontinuation. Prim Care Companion CNS Disord. 2018. https://pubmed.ncbi.nlm.nih.gov/30605268/
2. Papp A. Triggers and Characteristics of Brain Zaps According to the Findings of an Internet Questionnaire. 2022. https://pubmed.ncbi.nlm.nih.gov/35144325/
3. Internal Vibrations / Internal Tremors
   Blitshteyn S., Ruhoy I., Natbony L., Saperstein D. Internal Tremor in Long COVID May Be a Symptom of Dysautonomia and Small Fiber Neuropathy. Neurology International. 2024. https://pmc.ncbi.nlm.nih.gov/articles/PMC11768041/
4. Zhou T. et al. Internal Tremors and Vibrations in Long COVID: A Cross-Sectional Study. Am J Med. 2024. https://www.sciencedirect.com/science/article/pii/S0002934324004704
5. Small Fiber Neuropathy & Post-Infectious Mechanisms
   Oaklander A. L., Nolano M. Small-fiber neuropathy and post-infectious neuropathic syndromes. Neurol Clin Pract. 2019. https://pubmed.ncbi.nlm.nih.gov/31543773/
6. Azcue N. et al. Dysautonomia and small fiber neuropathy in post-COVID condition and ME/CFS. J Transl Med. 2023. https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-023-04678-3
7. Dr. Daniel Cameron: Lyme Science Blog. Lyme, POTS, and Adrenaline Surges Explained
8. Dr. Daniel Cameron: Lyme Science Blog. Ever wonder what is happening in the brain of neurologic Lyme disease patients who remain ill after treatment?