My patient had a long-standing history of Obsessive-Compulsive Disorder (OCD) that had been well-controlled for years. However, after being diagnosed with Lyme disease and completing a standard course of antibiotics, he began experiencing a significant resurgence of obsessive rumination. His mental health declined as he fixated on every symptom, convinced he would never recover.
Post-Treatment Lyme Disease Syndrome (PTLDS) and Worsening Symptoms
He was initially diagnosed with Post-Treatment Lyme Disease Syndrome (PTLDS) after completing treatment. His symptoms included:
- Chronic fatigue
- Joint pain
- Brain fog
- Heightened obsessive rumination
Despite seeking help from multiple specialists, his condition remained unchanged. His worsening OCD and persistent physical symptoms were attributed to PTLDS, but no further treatment was recommended. Over time, he became increasingly preoccupied with his illness, further amplifying his distress.
A New Perspective: Persistent Infection Considered
After months of searching for answers, I evaluated the case and considered that his ongoing symptoms—and his deteriorating mental health—could be due to a persistent Lyme disease infection rather than just PTLDS. With this new perspective, he underwent targeted treatment for Lyme disease and a previously unrecognized co-infection.
Improvement in Both Physical and Mental Health
As treatment progressed, his physical symptoms gradually subsided. More notably, his obsessive rumination about his illness also diminished. His cognitive function improved, and he was finally able to focus on other aspects of his life without being consumed by fear and uncertainty.
Key Takeaways: The Link Between Infection and Mental Health
This case highlights the importance of considering persistent infections in patients with PTLDS, especially when mental health symptoms worsen. For individuals with a history of OCD or other psychiatric conditions, untreated infections can trigger significant psychological distress. Addressing the underlying infection may not only relieve physical symptoms but also play a crucial role in restoring mental well-being.
