My patient had a long-standing history of Obsessive-Compulsive Disorder (OCD) that had been well-controlled for years. However, after being diagnosed with Lyme disease and completing a standard course of antibiotics, he began experiencing a significant resurgence of obsessive rumination. His mental health declined as he fixated on every symptom, convinced he would never recover.
Post-Treatment Lyme Disease Syndrome (PTLDS) and Worsening Symptoms
He was initially diagnosed with Post-Treatment Lyme Disease Syndrome (PTLDS) after completing treatment. His symptoms included:
- Chronic fatigue
- Joint pain
- Brain fog
- Heightened obsessive rumination
Despite seeking help from multiple specialists, his condition remained unchanged. His worsening OCD and persistent physical symptoms were attributed to PTLDS, but no further treatment was recommended. Over time, he became increasingly preoccupied with his illness, further amplifying his distress.
A New Perspective: Persistent Infection Considered
After months of searching for answers, I evaluated the case and considered that his ongoing symptoms—and his deteriorating mental health—could be due to a persistent Lyme disease infection rather than just PTLDS. With this new perspective, he underwent targeted treatment for Lyme disease and a previously unrecognized co-infection.
Improvement in Both Physical and Mental Health
As treatment progressed, his physical symptoms gradually subsided. More notably, his obsessive rumination about his illness also diminished. His cognitive function improved, and he was finally able to focus on other aspects of his life without being consumed by fear and uncertainty.
Key Takeaways: The Link Between Infection and Mental Health
This case highlights the importance of considering persistent infections in patients with PTLDS, especially when mental health symptoms worsen. For individuals with a history of OCD or other psychiatric conditions, untreated infections can trigger significant psychological distress. Addressing the underlying infection may not only relieve physical symptoms but also play a crucial role in restoring mental well-being.
Dr. Cameron
TY for this timely post about Lyme patients constantly ruminating about their illness. I am suffering with bartonella, babesiosis, as well as borelliosis. I’ve been treating with fluconizole azithromycin, tafenoquine and MB. Due to developing SIBO, I’ve taken a hiatus from all abx except tafenoquine and MB. My current symptoms are mainly bartonella related. What treatment would be most effective for this confection when I’m able to start back on abx. Currently taking lumbrokinase, biociden, nattokinase, JK, CC, cordyceps, red sage, Chinese skullcap, houtynea. TY for your efforts on behalf of the Lyme community.
I am sorry to hear they could not find an answer. Did your treatment other treatment including Mepron, Malarone, doxycycline, or Ceftin
thank you for this post. I have been dealing with extreme anxiety/depression for years. SSRI’s helped for many years but have not helped for at least 10 years. I was diagnosed with Lyme maybe 12 years ago. I have done lots of herbs and supplements. My main symptoms are anxiety, which leads to depression. I’ve also had SIBO on and off and have had chronic diarhhea for a year. Because of my gut issues I imagine that antibiotics would not be good for me. I’ve tried MANY things for the anxiety – and live a very healthy lifestyle. So, every now and then I come back to wondering if it’s actually caused by a tick pathogens….any advice as to where to begin? Thank you
I have fond antibiotics an alternative to a chronic illness in some patients if I start slower, use lower doses, and change therapy to include treatment for Babesia.
My 53 yr old son has so many mental symptoms . He was paraysised by a female pregnant tick when he was 4 years old had severe symptoms by 8 yrs old.. In Australia there are so few Lyme Drs
I hope you come up with a solution