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Diversity of Borrelia burgdorferi strains may explain treatment failures

Researchers have struggled to understand why 1 out of 3 Lyme disease (LD) patients remain ill on follow-up despite treatment. [1-3] Strain virulence, [4-11] treatment delays, [12-14] exposure to steroids, [12,15] and the presence of co-infections [16] have all been implicated as possible reasons for treatment failures.