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Could autonomic dysfunction lead to pain in Lyme disease?
In his review of autonomic dysfunction due to infectious diseases, Artal from the Neurology Department at Raigmore Hospital in the UK, writes, “Complex regional pain syndromes [CRPS] and reflex sympathetic dystrophy with regional sympathetic hyperactivity have also been reported in some patients with Lyme disease.” [1] CRPS is characterized by considerable pain (allodynia, hyperalgesia), edema, trophic changes of the skin and muscles and sudomotor disorders.
