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Children in the Netherlands remain ill with post-treatment Lyme borreliosis syndrome

Twelve out of 28 children with Lyme disease evaluated at an academic medical center in the Netherlands remained ill with post-treatment Lyme borreliosis syndrome (PTLBS). These 12 children presented with various complaints, including fatigue, general malaise and pain. There were no other medical explanations for their complaints and all were positive for Borrelia burgdorferi sl based on two-tier testing of C6-Lyme enzyme immunoassay (EIA) and IgG/IgM immunoblots. [1]