Adolescent with Lyme disease and depression holding his head

Lyme Disease and Depression: A Case of Treatment-Resistant Depression in a Teenager

Lyme Disease and Depression: A Case of Treatment-Resistant Depression in a Teenager Lyme disease and depression can be closely linked. Treatment-resistant depression in teenagers rarely prompts Lyme disease testing—even when accompanied by cognitive decline, academic failure, and a history of tick exposure. Neuropsychiatric symptoms—including depression, anxiety, irritability, and cognitive impairment—are increasingly recognized manifestations of neurologic […]

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