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Herxheimer reaction in a 13-year-old boy with Lyme disease

A Jarisch-Herxheimer reaction (JHR), also referred to as a Herxheimer reaction, was first described after initiating treatment for syphilis. This reaction is associated with the onset of new symptoms or a worsening of existing symptoms in patients receiving antibiotic treatment. The Herxheimer reaction has also been described in patients treated for leptospirosis, relapsing fever, and Lyme disease.

ALS or Lyme disease for a 63-year-old man?

Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease, is a progressive motor neuron disease.“In July 2018, that is, within six months, he developed paraparesis of both arms and also suffered from cramps in the shoulder girdle and hand muscles,” wrote the authors. “By August 2018, the patient was severely impaired in everyday life activities.”I first read about this case by Wirsching and colleagues in the journal Clinical Case Reports. His spinal test was positive for Lyme disease a high white count and positive labs tests for Lyme disease.  He was treated with a 3 week course of intravenous antibiotics without gains. The ...

ALS mimicked lyme disease. A case report.