January 24, 2021

After 37 years treating Lyme disease, I’ve seen motor neuron symptoms improve with antibiotic treatment in some patients while others don’t respond. Wirsching and colleagues describe a challenging case illustrating why Lyme disease should be considered in the differential diagnosis of ALS: a 63-year-old man whose ALS mimicked Lyme disease. Key Point: Lyme neuroborreliosis can