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Lyme disease persister theory

What Malaria teaches us about the Lyme disease persister theory

A recent study published in Nature Microbiology has revealed how malaria parasites survive in the human body for years without causing symptoms—offering powerful insights into the Lyme disease persister theory. Researchers from Weill Cornell Medicine, including Dr. Kirk Deitsch, found that Plasmodium falciparum—the parasite responsible for malaria—can evade the immune system by silencing its var […]

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What Is the Best Treatment for Lyme Disease?

What Is the Best Treatment for Lyme Disease?

When patients come to the office with Lyme disease, many have already been treated — yet they’re still sick. Others are newly diagnosed, overwhelmed by strange symptoms and uncertain about what lies ahead. The question most often asked is: “What’s the best treatment?” There’s No One-Size-Fits-All Answer Lyme disease can affect the brain, nerves, joints,

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Forget the Rash: These Are the First Symptoms of Lyme Disease.

Forget the Rash: These Are the First Symptoms of Lyme Disease

Patients with Lyme disease rarely walk into a clinic with the classic bull’s-eye rash or a clear memory of a tick bite. Instead, they often present with vague, nonspecific symptoms that are easy to overlook — especially when laboratory tests are negative or equivocal. By the time Lyme is considered, many patients have already seen

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What Happens if a Tick’s Mouthparts Stay in Your Skin?

What Happens if a Tick’s Mouthparts Stay in Your Skin?

It’s not uncommon for the mouthparts of a tick to break off and remain in the skin after removal. Fortunately, this rarely increases the risk of infection, including Lyme disease. Do Tick Mouthparts Increase Risk? No. If the tick’s body is removed, the risk of Lyme or other tick-borne infections does not increase. Most disease

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Lyme Disease and Joint Pain: Is It Debris—or a Missed Persistent Infection?

Lyme Disease and Joint Pain: Is It Debris—or a Missed Persistent Infection?

New research into Lyme arthritis (joint pain due to an infection with Borrelia burgdorferi) is challenging long-standing assumptions about what causes persistent symptoms after treatment. For years, many clinicians believed that when patients continued to experience swollen joints, even after treatment with antibiotics, the inflammation was simply due to an overactive immune system. The body’s

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Lyme Disease: One Teen’s Story of Struggle and Strength

A Patient’s Story Worth Sharing Today, I want to share a story that has stayed with me—a story about one of my teenage patients who faced overwhelming challenges after getting Lyme disease. His journey isn’t just about physical illness; it’s about resilience, emotional pain, and the life-changing power of support. Already Struggling—Before Lyme Even before

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Lyme Disease and Mental Health

My patient had a long-standing history of Obsessive-Compulsive Disorder (OCD) that had been well-controlled for years. However, after being diagnosed with Lyme disease and completing a standard course of antibiotics, he began experiencing a significant resurgence of obsessive rumination. His mental health declined as he fixated on every symptom, convinced he would never recover. Post-Treatment

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