Lyme Science Blog

Brain Fog and Cognitive Dysfunction in Lyme Disease: Symptoms and Causes Many patients with Lyme disease describe a frustrating and often frightening experience: they can no longer think the way they used to. Brain fog in Lyme disease reflects slowed thinking, poor concentration, and memory problems driven by neurologic and inflammatory changes. Concentration becomes harder. […]

7 Gut Clues Lyme Disease Might Be Involved Stomach pain. Nausea. Bloating. Sometimes the gut is one of the first systems affected. Normal GI tests do not always mean normal function. An 11-year-old girl had been struggling with stomach aches, poor appetite, and nausea for months. She was missing school, and every gastrointestinal test came

Early Warning Signs of a Lyme Flare: Symptoms Patients Notice First The early warning signs of a Lyme flare often begin before a full crash. Patients may notice subtle mood changes, strange fatigue, sensory overload, digestive changes, or a sudden sense that something is shifting. These symptoms are often dismissed—yet many patients recognize them as

Constipation in Lyme Disease: Why Gut Motility Slows Constipation may reflect autonomic dysfunction. Gut motility often slows in Lyme disease. Symptoms may fluctuate with neurologic stability. Constipation is a common and often frustrating symptom in people with Lyme disease. Some patients notice fewer bowel movements. Others experience hard stools, straining, bloating, or a constant sense

Chronic Lyme vs PTLDS: What’s the Difference and Why It Matters The chronic Lyme vs PTLDS debate is not just about terminology — it is about whether patients feel validated or dismissed. Many patients use chronic Lyme disease to describe ongoing fatigue, pain, and brain fog that PTLDS does not fully capture. The language clinicians

Immune Dysregulation in Lyme Disease: Why Symptoms Persist Immune dysregulation in Lyme disease may help explain why symptoms such as fatigue, pain, cognitive dysfunction, and sleep disruption can persist—even when tests appear normal and standard treatment has been completed. Many patients improve after Lyme treatment but do not return fully to baseline. Increasingly, research suggests

When Medicine Says There’s Nothing More to Do “Nothing more can be done?” Symptoms may persist despite normal testing. Care should not end when uncertainty begins. What does it really mean when you’re told there is nothing more to do—yet your symptoms continue? I wrote this because I often meet patients who have been told