Lyme Science Blog
May 20

My Lyme Disease Patient Got Worse on Antibiotics—Until We Adjusted the Dose

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He was ready to quit treatment.

The antibiotics were making him feel worse, not better—nausea, fatigue, and a sense that his body was shutting down. He told me, “Doc, I don’t think I can keep doing this.”

I knew we needed a new approach—but not necessarily a new medication. Instead, I asked:
What if we adjusted the dose?


⚖️ When Less Is More

Instead of the standard full dose, we lowered it—just enough to reduce the burden on his system, while still targeting the infection. It was a small tweak, but the impact was big:

  1. His side effects eased within days
  2. His energy improved
  3. And most importantly, his Lyme symptoms began to resolve

🧩 Why Individualized Treatment Matters

This case reminded me that Lyme disease treatment isn’t about pushing patients to the edge—it’s about meeting them where they are. If a full dose overwhelms the system, patients can’t heal. But the right adjustment? That can unlock progress.

Every patient’s journey is different. Sometimes, it’s not about starting over—it’s about finding the dose that works.


💡 A Gentle Nudge, Not a Full Detour

This patient didn’t need a new medication or a brand-new protocol. He just needed someone to see the bigger picture and make a targeted change. That one adjustment helped him stay the course—and ultimately, heal.

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