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Dr. Daniel Cameron

Dr. Daniel Cameron

Doctors recognize Lyme disease in a patient with kidney disease

The article, “Chronic Lyme borreliosis associated with minimal change glomerular disease: a case report,” cites four published papers describing kidney damage in Lyme disease patients. The papers consisted of 4 cases of membranoproliferative glomerulonephritis (MPGN), a case of crescentic and IgA-deposit nephropathy, and a case of membranous nephropathy. [1] In another case, the authors describe […]

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“Fake news” charges do not give credit to the Lyme disease community

by Daniel J. Cameron, MD MPH Polly Murray’s children and neighbors suffered from Lyme disease rather than Juvenile Rheumatoid Arthritis. Alan Steere described a cluster of adolescents and adults with Lyme disease in Lyme Connecticut. William Burgdorfer discovered Borrelia burgdorferi in the midgut of the Ixodes scapularis tick. James Krause discovered Babesia microti in the

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Don’t count on a relapsing fever to diagnose Borrelia miyamotoi

Despite having the genetic apparatus, B. miyamotoi typically does not manifest with a relapsing fever. “Although evidence of antigenic variation, which drives the relapsing course of other relapsing fevers due to borrelia has not been demonstrated clinically or in an animal system thus far for B. miyamotoi [2], it has been shown that this species

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Borrelia miyamotoi disease can be added to list of traveler’s concerns

Doctors described a case of BMD in a previously healthy 63-year-old American man living in Japan. “He reported being bitten by ticks several times while staying with his family at his summer house in the state of Minnesota in the USA from July 25 to August 9, 2013,” according to Oda from the Division of Infectious

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Questions linger on the efficacy of the Lyme disease vaccine

The OspA vaccine trial was 78% effective at preventing a culture confirmed erythema migrans rash. But the vaccine was only 48% effective at preventing what the authors referred to as “possible Lyme disease.” “Possible Lyme disease was defined as a flu-like illness (fever, chills, fatigue, headache, joint or muscle aches) with IgM or IgG Western blot

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NEUROLOGIC LYME DISEASE PATIENTS

Ever wonder what is happening in the brain of neurologic Lyme disease patients who remain ill after treatment?

by Daniel J. Cameron, MD MPH The authors found 13% of patients with a spinal tap positive by both cerebrospinal fluid pleocytosis and Borrelia-specific antibodies remained ill for more than 3 months after treatment. Meanwhile, 33% of Lyme neuroborreliosis patients with Borrelia-specific antibodies detected in cerebrospinal fluid and 43% of Lyme neuroborreliosis patients with pleocytosis

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Borrelia burgdorferi activates human astrocytes cells in culture

by Daniel J. Cameron, MD MPH According to the authors, “If uncontrolled in the context of neuroborreliosis, the astrocyte response could lead to long-term injury in the CNS.” Researchers identified changes in gene expression within 48 hours of infecting cultured astrocytes with Borrelia burgdorferi (Bb). “Understanding how these changes are maintained over time will be

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