When Lyme disease causes a positive test for mononucleosis

False positive serologies for Lyme disease have been previously reported in patients with acute infectious mononucleosis. However, a recent paper describes two cases in which Lyme disease was misdiagnosed as mono based on false positive serologies for the Epstein-Barr virus (EBV).

 

by Daniel J. Cameron, MD MPH

In the article, published in the journal Clinical Infectious Diseases, Pavletic, from the National Institute of Mental Health, reports “two cases of false positive Epstein-Barr virus (EBV) serologies in early-disseminated Lyme disease.”

In the first case, a 16-year-old male from Virginia developed fatigue, myalgias and three brief episodes of fevers over an 18-day period. He was diagnosed with acute infectious mononucleosis based on a positive viral capsid antigen (VCA) IgM and negative VCA IgG.

It was not until 17 days later with the onset of multiple erythematous rashes and right-sided peripheral facial nerve palsy that doctors diagnosed the young man with Lyme disease. Laboratory evaluation revealed a positive C6 peptide ELISA index of 6.02 and a positive IgM immunoblot. He was prescribed a 4-week course of doxycycline and recovered.

“Repeat VCA IgG, VCA IgM and EBNA were negative, indicating that the initial VCA IgM was falsely positive,” according to Pavletic.

In the second case, an avid biker from Maryland presented with a six-day history of fatigue, fever, myalgias and headache. Lyme disease was diagnosed the next day based on multiple erythematous rashes. Lyme serologies were positive by ELISA, IgG and IgM immunoblots.

Twelve days into her illness she tested positive for mononucleosis with a positive VCA IgM, VCA IgG, EBV early antigen, EBNA IgG, and positive monospot.

The fever resolved and the rashes faded with a 21-day prescription of doxycycline. The recovery was complicated by a right upper trunk brachial plexopathy. “The pain resolved and the weakness improved over the next six months,” according to Pavletic.

“Three and a half years later, repeat VCA IgG and EBNA were positive, and VCA IgM was negative.”

According to the authors, both cases were initially misdiagnosed. “Here we present two cases where early manifestations of Lyme disease were initially misdiagnosed as acute EBV infection due to positive VCA IgM results.”

The authors touched on the difficulties interpreting acute mononucleosis testing. “While isolated VCA IgM may indicate early acute mononucleosis, the test can be nonspecific, especially when the likelihood of acute EBV infection is low.” Pavletic adds, “Immune activation with other pathogens can also result in a false positive VCA IgM.”

The second case was difficult to interpret given the positive monspot, heterophile and VCA IgM tests. “In this case, we cannot exclude that the positive VCA IgM could be due to subclinical EBV reactivation, which has little clinical relevance in immunocompetent individuals,” states Pavletic, adding, “Heterophile antibody tests are known to have false positives due to acute infections, autoimmune diseases and cancer.”

In practice, Lyme disease and mononucleosis are common conditions that share similar symptoms. The authors’ two cases remind the reader of the need to consider Lyme disease even if initial serologies suggest mono.

 

References:

  1. Pavletic AJ, Marques AR. Clin Infect Dis. 2017 Apr 4. doi: 10.1093/cid/cix298.


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Bobbie ann williams
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My daughter has lyme and coinfections, came off all meds for lyme in april. Few weeks later had a sinus infection and was treated. About 3 weeks later wound up in hospital running a 104 fever. After almost 2 weeks in one hospital was transferred to another hospital. Was given an Ivig treatment and fever finally was gone. Long story short, she had a very severe case of ebv and mono. She also had many other issues happen caused from the ebv. Is PCR testing better than testing for the antibodies of ebv? Having a conflict between our llmd and… Read more »

Joy pehl
Guest

In 2017 after hiking i noticed a tick on the back of my leg . I pulled on it thinking i got it off . 2 days later my leg still hurt and went to my family doctor. Seeing it was on the back of my leg i never noticed the bullseye rash . The doctor lanced it and removed the head …horribly painful for such a little pin dot . Immediately I was put on doxycycline for 30 days twice a day . It was like i had the flu and very sick to my stomach. The doctor took… Read more »

Veronica
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Veronica

I had Lyme disease in 2010 but we caught it on time, I was treated and felt normal again for 5 years, in 2015 I got tired and anxiety attacks went to ER and they found Mono, its been 4 years and still not recovered I have seen so many doctors and I haven’t found any answer or diagnosis for my symptoms, feeling exauhusted all the time and big pressure in my head, that makes it vibrate when I seat, I have to rest all the time if I stand for long, I keep active but I get so exhausted.… Read more »

Brian
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Brian

Please read LAB 257. This was an eye opener for myself and my wife who has late stage Chronic Lymes disease and has suffered terribly. It is very sad to read but will provide the truth behind Lymes, West Nile Virus etc… Keep in mind that Lymes mimics hundreds of other diseases.

Cynthia
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Cynthia

I went from Doctor to Doctor for a year and half trying to find out what was wrong. I had dizzy spells, headaches, Memory loss, Stinging in the head, burning skin, fever occasionally, Joint pain, feeling like something is crawling on me, feeling like something is stinging me. Stinging in both my eyes and tongue. Sometimes stinging on my nose and lips, burning up at night, feeling tired all time and hurts to walk. I was diagnosed with Chronic Lyme disease with Neuropahty. I had 21 day oral antibodies and then two months later had 4 weeks Picc line of… Read more »

daniel
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daniel

thank you for your reply.
What do you make of the WB results that seem to be positive (or cross reactive with previous positive EBV??) which was then followed by a negative Lyme IgG/IgM ab Result <0.91?

Daniel
Guest
Daniel

Dr. Cameron, I need help understanding the following: Sept. 2017 I was very fatigued for a couple of weeks, went to ENT who ordred EBV: Result IGM 46.50, IGG 74.10 Both positive. Eventually I got much better within a couple of weeks with proper care. A couple of months later, I had a couple of odd symptoms, a finger twitching every once in a while and another a finger feeling “heat”. I thought I had a pinched nerve in the elbow or perhaps carpal tunnel. Went to see neurologist, he ordered Lyme test: Lyme WB Blot, Serum: Lyme AB IgG… Read more »

Kent
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Kent

I have been diagnosed with ebv Huge allergies that set it off. That being said i have had what i believe to be lyme 2 or 3 times now and had west nile in 07. First lyme in 03. Every symptom was text book. No doctor where i live knew about it at the time so i found one that would give me doxy. 28 days. Got rid of all symptoms. Twice more every 5 to 7 years i jave had this. Last in sept. 18. Doxy again. Had blood teat in jan 19 for the first time for Any… Read more »

Jane Woods
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Jane Woods

Mono is a contagious illness that’s caused primarily by the Epstein-Barr virus (EBV). Most of the time, medications will not help speed recovery (though some painkillers may ease symptoms). But knowing what precautions to take during the healing process can go a long way in helping you feel better sooner and avoid complications. It’s not known exactly how long someone can be contagious after they get the virus. People can shed the virus in their oral secretions for several years, and the shedding is intermittent. You can also refer to this article which states all the necessary details about mononucleosis… Read more »

Dee
Guest

Tick bite (thought spider bite) back in 1992. Weeks later slurred speech, intense head vise like pressure, weakness in limbs, thinking off dizzy(sea sickness feeling)These symptoms plus a drofoot lasted on and off for over 20 years with no explanation. In and out of emergency rooms and over 6 months at Mayo, UCSF, Stanford, Cedars still with no diagnosis. 50+ docs mostly neurologists, Multiple abnormal EMG’s, Abnormal Spect showing brain vasculitis but normal brain MRI. I was NEVER tested for infectious causes (viral or bacterial) during this time only MS which was ruled out. Finally IGENEX IGM pos. I8,31,34,41,45 and… Read more »

Scetin
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Scetin

I got sick in the beginning of December and went to the doctor. She did flu and strep tests as i had muscle pain headache and sore throat. They were both negative and she order more tests. A week later test results came back with positive mono and elevated CRP. My doctor said you don’t look like you have mono and we should check Lyme. A week later i was diagnose with Lyme. IGG all negative and 39 and 23 bands on igm were positive. Could this be false positive? I suspect that i have undiagnosed arthritis since i have… Read more »

Carolyn Johnson
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Carolyn Johnson

Dr Cameron Thank you ever so much for the work you are doing online. You are a Godsend. Your replies to us re Lyme and mono made perfect sense. We continued with Doxi even though the Dr said 2 weeks was enough. It made no sense to us at first but since we live in an area that is rampant with ticks, have 4 shelties that have all been treated for Lyme I am surprised my doctor would not see the possibility of that being the main cause. I also put my husband on a regime that I have had… Read more »

Brian Johnson
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Brian Johnson

This site was an amazing find. Starting October 19th, I ran a fever of 103F (39.5C) for 5 days straight with severe chills, constipation and tiredness. On the 2nd day, I went to the ER and was told by the doctor it was the flu and to treat the fever with acetaminophen and ibuprofen, and also that my platelets were slightly low (140). After the fever broke I started feeling better but was still tired, which I assumed was normal after what I went through. On November 3rd, the fever came back at the same temps as did other symptoms.… Read more »

Carolyn Johnson
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Carolyn Johnson

My husband (52) came down with a fever of 38 AND 39. I took him to emergency and they supposed it was the flu. Told him to take Tylenol for the fever. The high fever went away but returned a week later. We went back to emerg. same diagnosis and this time Tylenol and Advil again. The fever was less for 3 days ant then back to 39, nite sweats and chills..We went to a different hospital and they took many tests. I noticed a red blotch on his back and then a few more but not the bulls eye… Read more »

Anne ROBERTSON
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Anne ROBERTSON

Hello Dr. My daughter is pos for cronic bartonella. She is currently in Denver for school and is very sick. swollen glands, face, super cogested, major leg pain, eyes are crusty and goopy. She went to the ER and they said it was either Mono ( which there is no test for) or its viral. My kiddo can eat nor has the energy to do anything. we have tested her for Mono before she was diagnosed with Bart and she was pos for being esposed to it but not currently having it. She never had any signs of mono before… Read more »

Sara Moulton
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Sara Moulton

I had a tick bite then 10 days later developed very swollen glands. Two weeks later, still swollen glands, IGG and IGM neg for Lyme, but began 100 mg doxy. Two weeks later, no change in swollen glands. Mono test positive. Doctor says no Lyme, stop doxy, mono only. I am concerned that I have both, and that the mono is caused by Lyme reactivating or allowing its development. Is this a likely scenario?

Lon Honzell
Guest
Lon Honzell

Years ago I was diagnosed with Mono, severe case. Was hospitalized for three days, getting well? 18-20 Years later was diagnosed with MS, Which I still have. was tested for Lyme disease, not found. Through out this process I kept telling doctors I thought it was something else. No it’s MS, MRI’s shows it? Still having my doubts, what was I to do. Except keep taking that non working MS Medication.
Until much later, Now. I have been doing some personnel research, coming to the conclusion it is Lyme Disease. ?

Mike
Guest
Mike

I was bitten by a tick in April 2018 and developed fatigue, night sweats and joint pain in knees, hands and feet 3 weeks later. I was prescribed 3 weeks of Doxycycline. The night sweats stopped but the fatigue and joint pain have remained. I had bloodwork 2 weeks ago and was told I have acute active EBV. My IgM for 39 and 23 were positive for Lyme, Lyme IgG/IgM is .94 ISR, quant IgM is 2.01 index. I was told I don’t have Lyme, just EBV. Is it possible I have Lyme, could the Epstein-Barr cause the joint pain… Read more »

Vivian Verrier
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Vivian Verrier

I got a bullseye rash 3 times in 2005. Same spot. Drs. Said noone can get a bugbite on the bra line. 13 years later I FINALLY may get treatment for Lyme. Lots of positive tests. Not ALL . Was told about EBV. Recently. Lyme ruined my life. Destroyed my body and spirit..wonder if 4 weeks of doxycycline will work. So many years later.

Shelly Willis
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Shelly Willis

My 2 yr granddaughter had an engorged tick removed ,followed by rash near bite, high fever ,vomiting diarrhea and swollen lymph nodes in her neck. Started amoxicillin ,4 days after removal of tick and then amox-clav a few days after finishing the amoxicillin.high fever stopped but started complaining of sore hands knees elbows neck and back also complained of tummy pain would wake up in the middle of the night crying due to the neck /back pain and her hands and fingers were hurting.wrnt back to Dr. Asked to be tested for Lyme disease and any other illness that could… Read more »

Rita
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Rita

How does CMV virus compare to Ebv? Could they be mistaken? Also I had shingles, HPV virus, what’s the best way to go about testing for all these issues, my mris ,show pineal cyst ,5.5mmx6.5mmx7.5mm, 1-along with felt to be in normal limits-signal in mass cell, mild right side mastoiditis, , yet..2 yrs later MRI has expanded compared to original mri-maistoidtis right side, 2- prominence in surrounding area soft tissue nasopharyngitis, and mild prominence of cystic adrenoid of lymphoid tissue? I know these aren’t Lyme, but with constant sinus issues, and trouble swallowing without choking often lately, I wonder if… Read more »

Rita Shaw
Guest

Hi everyone, it’s Rita Shaw again, I’m really confused. Like I said 3 not 2 Elisa came back high positive, 1.11, 1.25, 1.43 But all western blot negative-Dr’s were shocked because I had all the symptom of Lyme, later test show high postive, ebna-Igg& vca-Igg 2006 , EBV, though clearly symptomatic, blood lab thought to be a passed on maternal infection? At 14, I was hospitalized for severely high fever, enlarged spleen, and liver?( And always had history since baby of tonsillitis (removed at 2)strep, bronchitis, pneumonia, laryngitis, swollen lymph nodes, etc, every years once or more.ever since) in 2006-… Read more »

Beth
Guest
Beth

is it possible to have mono and Lyme disease? my daughter is 14 and was told by her dr. She has Lyme disease, mono, and her gallbladder isn’t working if anyone can give me info please let me know

Carl Tuttle
Guest
Carl Tuttle

The Marques paper talks about false positive Epstein Barr serology but many believe outer surface protein A of the Borrelia spirochete causes immunosuppression for the following reasons… “Spirochetes disseminate to the lymph nodes, bone marrow, spleen and brain within a week of infection [1]. Lymph node germinal centers, where B cells are supposed to mature and be assigned an immune system function, are rendered incompetent [2] “B-cell AIDS” (1) https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1002066 (2) https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1004976 I truly believe that Lyme disease is immunosuppressive allowing latent viruses to rear their ugly heads and the positive EBV tests in the Marques case studies were reactivated… Read more »

Carl Tuttle
Guest
Carl Tuttle

The Marques paper talks about false positive Epstein Barr serology but many believe outer surface protein A of the Borrelia spirochete causes immunosuppression for the following reasons…

“Spirochetes disseminate to the lymph nodes, bone marrow, spleen and brain within a week of infection [1]. Lymph node germinal centers, where B cells are supposed to mature and be assigned an immune system function, are rendered incompetent [2] “B-cell AIDS”
1.
http://JOURNALS.PLOS.ORG/PLOSPATHOGENS/ARTICLE?ID=10.1371/JOURNAL.PPAT.1002066

2. http://JOURNALS.PLOS.ORG/PLOSPATHOGENS/ARTICLE?ID=10.1371/JOURNAL.PPAT.1002066
CARL TUTTLE
LYME ENDEMIC HUDSON, NH

Colonyresidents
Guest
Colonyresidents

How does this work, since we all know that the OspA that is released by the spirochetes damages the immune system and allows all kinds of other pathogens to reactivate?

Dacia
Guest
Dacia

Interesting blog– I’ve never made that link, although like others posting here, I’ve had both mono and Lyme/Babesia. When I was a first-year student in college, my roommate and her boyfriend both came down with mono. I wasn’t surprised when a couple of weeks later I came down with something awful: 10 days of drenching night sweats, 103-104 fever, extreme muscle weakness. But I tested negative for mono. A few months later, a circular rash appeared on the back of my thigh: this time the doctor told me it was ringworm, and sent me home with a fungicide cream. The… Read more »

Dawn
Guest
Dawn

I read mixed rewiews regarding the use of antibiotics for chronic lyme. Any one have experience using long-term antibitotics?

Joyce Dahlberg
Guest
Joyce Dahlberg

Yes I am. I personally do not believe you can get better without some. The biofilm is key in killing this smart and stubborn bacteria. Must also use supplements, healthy eating and so much more. There is no one simple cure it is a combination of lots including detoxing like crazy. I know too many that are on herbs only and they so not seem to get better. I do know one that did but I think it is before she caught it right away. How long before starting treatment is the key. I knew mine needed to include antibiotics… Read more »

Jennifer
Guest
Jennifer

When I was 20 I was diagnosed with mono. The pediatrician said it was the worst case he had ever seen. I could barely get out of bed for a month. After that could no longer stay awake late at night like I was accustomed to. In my early 20’s I developed arthritic symptoms. I came to accept that my joints would always hurt. In my 30’s although I seemed otherwise healthy, I could not kneel down to play with my kids. In my 40’s I was diagnosed with Lyme. I had all sorts of neurological problems including not being… Read more »

James
Guest
James

When I finally tested positive for lyme in 2010 I also tested positive for EBV

ilene
Guest

My daughter, 13 years old now, was recently diagnosed with mono after high fever and swollen glands for weeks at a time. 3 summers ago she was diagnosed with lyme after coming home from summer camp with muscle and joint aches, severe weakness and a bulls eye rash. After a day of docyclone, she threw up and it threw her into a long term panic attacks for the fear of throwing up again. After therapy. After the recent diagnosis of mono, I insisted the Dr to run the lyme test while they were running the other levels after coming across… Read more »

Rita Shaw
Guest

I dont understand I was tested in 2009 2 different times and my Elisa-Lyme reactive was high positive both times…but western Igg and Igm were negative..with comment Antibodies to less than 2 of 3 significant B.burgdorfebe. proteins detected additional specimen should be submitted in 2-4 weeks.. Rheumatoid factor was 20.0 normal 0.0-20.0 I had all lyme symptoms for 2 yrs after camping tripin 2007…in 2012 high ebv tilters? Also get flu like symptoms, though I was diagnosed fibromyalgia and chronic fatigue after lyme was negative. I have also been diagnosed Anterior Pituitary disorder..migraines, and now no false tb skin test..in… Read more »

Joyce Dahlberg
Guest
Joyce Dahlberg

Never too late. for me 37 years untreated. Do not go by the regular offered testing. Too many numbers were purposefully eliminated as too many people would test pos. This occurred in 1994 after 2 viruses were determined to be bacteria. Get the IGENEX test that gives the numbers that you can evaluate and research yourself too. CDC and many others do not want people to get diagnosed to start out with. You have to be your own advocate. DO NOT RELY ON TRADITIONAL MEDECINE.

Kelly Kutrufis-Lee
Guest
Kelly Kutrufis-Lee

Good Afternoon,

I was recently diagnosed with mono- EBV Ab VCA, IgG = 559.0 on 9-21-17 and tested negative for Lyme total An test/Reflex-lyme IgG/IgM Ab= <.91 on 8-9-17. I am still having problems and I'm very frustrated and worried that my diagnosis is wrong. I would like to know where everyone was finally diagnosed with Lyme's? Or what steps I should take next? Currently I'm seeing my general practitioner.
Thank you for your help!!

Susan
Guest
Susan

So my son had mono in early 2015. He had a very bad case that was undiagnosed because he didn’t have sore throat or swollen lymph nodes, just crazy fever, drenching sweats for 9 days and fatigue, which doctors ignored. He got sort of better, played basketball and wound up in the hospital where they finally diagnosed him with mono after a positive monospot, atypical lymphocytes =31, and a very enlarged spleen (19cm). He was very sick with fevers for another two weeks did get the awful sore throat and lost 20 pounds. He’s never been well since and seems… Read more »

Laura
Guest
Laura

Wow, this is an informative article and I appreciate the responses from your readers as well. Based on my incapacitating fatigue, my Nurse Practioner had me tested for EBV when I was getting labs to check my thyroid levels. Upon receiving the news that I was having a severe EBV reactivation episode, I asked to be tested for CMV and for Lyme. CMV was negative, but I was confirmed to have Lyme (this was on 7/5/2017). I had been so ill that I had to resign from my job in mid-June and have not been able to work. I was… Read more »

Mary K Hull
Guest

Two weeks ago my arm, chest, and hands started to hurt and I noticed clusters of puss pimple like rashes on the same right arm and palm. In a few days the pain was so awful I ended up in the then emergency room. I am a 54-year-old mother of 4 and I have never known such pain. My right knee started to hurt. I used a cane most days. I have been tested for everything including STDs and parvo. I have also developed vertigo. The only thing that has come back positive is mono. What do I do? This… Read more »

K Murray Leisure MD
Guest
K Murray Leisure MD

Consider also right-sided body shingles, VZV. Interesting that some cases of Lyme have been followed by Varicella zoster virus (shingles, reactivated chicken pox virus) blocks of rash within the same nerve distribution, the same dermatome, as the tick bite. Perhaps the arachnid / tick bite activated VZV usually latent in the spinal column to erupt in the limbs peripherally?

Jackie
Guest
Jackie

I got lyme from a spider bite and so did the NP who’s treating me. (She came from a rheumatology practice and left because she didn’t agree with their diagnosis and treatment protocols.)

Helen
Guest
Helen

38 years ago while working as a RN I became so totally exhausted to the point that I could barely get out of bed and had to sleep. I was a very healthy active woman at 26 years old. The lab called me and first told me I had mono then, that I was pregnant. I was very happy since we were planning to have a baby, our first of two daughters 13 months apart. I was also happy that there were two “reasons” why I was completely exhausted yet I still felt I was TOO exhausted. Not until 11… Read more »

Stacey
Guest
Stacey

Thanks for sharing everyone. I gave birth 17 months ago and kept thinking I felt so tired from the new house, new baby and work. Never once did i think I was sick. Just always tired. Then I got dizzy spells but I had suffered with migraines for three-four years before my daughter so I assumed this was my body reacting to migraines (even though I got those in check now). I went back to my naturopathic doctor who helped with the Migraines and she did a full work up. Same as she had done in 2015 before I got… Read more »

Joyce Dahlberg
Guest
Joyce Dahlberg

So many of the stories could be mine. I got sick in 1977 or 1978 but did not understand what the 1st symptoms meant. SO 37 years later I am able to recall as my mind has returned due to being treated for Lyme starting in 2016. 2015 was a hell of a year with heart palpitations, pains, pins and needles and so much more. As getting better (at times feeling worse) symptoms emerged. The saying is that the first symptom you had is the last one to go away. Well I started to have shortness of breath, sneezing and… Read more »

Kathleen
Guest
Kathleen

Mono at age 18. Lyme and Mono at age 55 and early onset Alzheimer’s symptoms at age 55. Lyme test was positive and I have been recovering my health since 2012. There are no more symptoms of early onset Alzheimer’s and I am grateful that my family doctor, at the time, was able to prescribe the right antibiotics for the necessary time to get me healed. I have also changed my diet, exercise and lifestyle around to be healthier, because thanks to Lyme and Mono, I can no longer take a break from staying on top of my health, or… Read more »

Debbie
Guest
Debbie

What antibiotic and how long were you on it?

Lynne
Guest
Lynne

Interesting indeed. I have an Igenex IgM result with 31+, 41++ and 45+ And have been told I am negative for Lyme disease. Of course that is CDC negative. I still have unbelievable fatigue and joint pain that is nearly unbearable 24 hours a day. The fact that I live in NY makes it that much more difficult. No one seems to want to treat this and all I want is to feel better.

Joyce Dahlberg
Guest
Joyce Dahlberg

#31 is staph aureus bacteria. More or less contaminated water. # 41 is the spirochete (not necessarily Lyme). # 45 I believe is osteomyelitis as I have that # as a previous infection/together with # 30 as a European strain. Yes I got osteomyelitis as a child after getting the BCG vaccine in France. Current infection is for me #31, #34 and # 41. This is chlamydophila C pneumonia from staph aureus infection. #34 is a deeper infection of lung and yes the infection affected my brain. This staph bacteria favors higher oxygen level. The #34 is a deeper fungal… Read more »

Becca
Guest
Becca

So interesting! My daughter is 9 and had tests run through IGenex. Showed ++ on 41 band of IgG and IgM but gave a negative overall result. Doctor tested her for EBV and it came back positive. She has severe joint pain, tummy aches, fatigue, weight loss, and random fevers on occasion. When I asked him what to do with the EBV result, he said “Lots of rest.” He assured me she did not have Lyme and that she has had EBV for “quite some time.” Her symptoms have been going on for 18 months. No known tick bite but… Read more »

Anna
Guest
Anna

Not all doctors are correct and when it comes to our children we know what is right and a lot of us go by our gut feeling because we know our children better then a 5 minute exam and a test or two. I pray you don’t accept the doctor’s answer and demand she be retested by another facility or by a doctor specializing in Lyme’s Disease. 18 months of symptoms is way too long for your little girl! Do not stop testing or seeing doctor after doctor until she is diagnosed. I wish you and your family the best… Read more »

Carolyn
Guest
Carolyn

My daughter’s Ilad said the sicker or more chronic the Lyme disease the harder it is to test positive. Her IGenex test came back inconclusive for Lyme but positive for Babesio and other coinfections . Her blood was also sent to a lab in Germany where the Lyme was positive along with the coinfections. She also tested positive for EBV. She now has Chest port and receiving Iv antibiotics but improving.

Joyce Dahlberg
Guest
Joyce Dahlberg

Did the test show #31 or even # 34. If #31 that is staph aureus USA strain 300, potentially USA strain 252. # 34 is a deeper infection. These two go together and favor lung and brain. #34 has elastic type protein that goes to brain an lung as it prefers higher oxygen levels.

Joyce Dahlberg
Guest
Joyce Dahlberg

find out the other numbers. # 31 is staph aureus bacteria which is opsA and is USA 300 strain. Possibly even USA strain 252. # 34 (opsB)is also a deeper infection that goes together with the #31. #41 is the flagella and not necessarily a tick spirochete. Staph aureus is a spirochete too. Get the Igenex numbers. The mentioned #31 and #34 were like eliminated or manipulated by the CDC after the 2 bacteria (mycoplasma and chlamydophila C pneumonia) were accidently found to be bacteria. The smallest known bacteria to this day. The CDC does not want people to know… Read more »

Christina Harrison
Guest
Christina Harrison

I’m 14 and my mom has severe late stage lyme disease and the epstein barr count was off the charts. She is 46 and has had lyme disease since she was in 7th grade. She is really depressed all the time and saying that she just wants to die. She hasn’t cooked in months and has quit her job. She is really sick and tired and her joints hurt. I want to try to help her get treatment but I don’t know how or what to do. I want to get a job to help but I don’t know where… Read more »

Christelle Maginot
Guest
Christelle Maginot

I’m so sorry to hear your mom is sick. Lyme is difficult for everyone in the family. It took me 8 years to get to remission, and even though I relapse regularly, I have managed to keep things under control and go back to a “regular” life. So there is hope. The trick is to find a Lyme-literate doctor and be on the right mix of medication for your mom’s individual case. Recently, Disulfiram (a drug originally developed for alcoholism) has been proven to eradicate [chronic] Lyme. There’s a doctor in NY who has had over 90% of success with… Read more »

Julie
Guest
Julie

I always wondered if my EBV diagnosis when I was 16 could have been Lyme’s, since, it was so severe I was sick for years and my fatigue, neurological problems continued up to and have continued thru & after I diagnosed w Lyme’s and co-infections at age 35.

Destiney
Guest
Destiney

That sounds exactly like me I was finally diagnosed yesterday with Lyme…as well as Babesia, Mono, Candida and numerous other things…i missed the last month of 7th grade due to mono???? And my physical and mental health continued to decrease…i wonder if it was Lyme the entire time…We were ALWAYS outside…sports camping playing…..i feel so overwhelmed

Elysa
Guest
Elysa

3 weeks after a tick bite, I went to the doctor with fever, aches, chills, joint pain and exhaustion. ELISA came back negative but the MonoSpot lit up like a christmas tree. For the next 5 years I was told I had Post Mononucleosis Syndrome, Fibromyalgia, MS, Cancer, Depression… I was able to find an LLMD through ILADS.org who ran a Western Blot among other tests. They came back postive for Lyme and Babesia. I’m now going on my 9th month of treatment but I’ll be living with the damage for the rest of my life.