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Lyme Science Blog

Lyme Persisters: Why Some Patients Stay Sick After Treatment

Lyme Persisters: Why Some Patients Stay Sick After Treatment

You finished treatment. The antibiotics are done. Your doctor says you’re cured. So, why do you still feel terrible? For many patients, the answer may lie in Lyme persisters — dormant bacteria that survive antibiotic therapy and can reignite symptoms long after treatment ends. The Role of Lyme Persisters For many Lyme patients, fatigue creeps

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Lyme and PANS in Teens: The Boy Who Changed Overnight

Lyme and PANS in Teens

He was a healthy 16-year-old, active in school and sports. Within days, he seemed unrecognizable. His story shows how Lyme and PANS can suddenly change a teenager’s life. Once outgoing and confident, he suddenly became anxious, irritable, and trapped in repetitive rituals. Teachers noticed his handwriting deteriorated, his grades plummeted, and he withdrew from friends. “It

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Physician Reluctance in Lyme Treatment: Risks for Patients

Physician Reluctance in Lyme Treatment: Risks for Patients

Dr. Sarah reviewed the file carefully. Her patient exhibited all the classic symptoms of Lyme disease and had been exposed to ticks. But the test was negative. She knew from experience that early Lyme tests miss up to 50% of cases, yet she hesitated to make the diagnosis. This kind of physician reluctance in Lyme

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Lyme Disease and Long COVID Patient Guide

Lyme, Long COVID, or Both? Making Sense of Persistent Symptoms

Three years after beating Lyme disease, Jennifer tested positive for COVID-19. Months later, the same crushing fatigue, brain fog, and joint pain that she experienced with Lyme had returned. Was it Long COVID — or Lyme again? Doctors disagreed, and meanwhile she felt worse by the day. This scenario is increasingly common. Many patients discover

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overlooked-lyme-disease-clues

His Parents Overlooked These Lyme Disease Clues

Act 1: A Missed Beginning Jake went from star athlete to unable to climb stairs without his heart racing. His parents searched for answers for two years before anyone mentioned Lyme disease. With no tick bite or rash, his parents and doctors didn’t recognize the early warning signs. Act 2: The Diagnostic Odyssey Jake’s family

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Risk Factors for Chronic Lyme Disease

While many people treated for Lyme disease recover completely, a significant number develop chronic Lyme disease with persistent symptoms that continue long after standard antibiotics. These patients often report having ongoing fatigue, pain, sleep disturbance, neurological changes, and emotional strain that disrupts their lives. Understanding the risk factors for chronic Lyme disease is important for

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Low-Dose Naltrexone for Lyme: What We Know (and Don’t)

Low-Dose Naltrexone for Lyme: What We Know (and Don’t)

Low-dose naltrexone (LDN) has gained growing attention as a potential supportive therapy for people with chronic Lyme disease and persistent symptoms that may not fully resolve with antibiotics. Originally developed as a treatment for opioid and alcohol dependence, naltrexone in much smaller doses appears to have immune-modulating and anti-inflammatory effects. For patients struggling with lingering

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