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Lyme Science Blog

Why Patients With Lyme Disease Feel Exhausted Despite Sleeping

Why Patients With Lyme Disease Feel Exhausted Despite Sleeping

Many patients with Lyme disease describe the same experience: they sleep through the night yet wake feeling depleted. This is not about sleep duration — it is about biologic fatigue and impaired recovery. Feeling exhausted despite sleeping often reflects what clinicians describe as non-restorative sleep — a state in which sleep occurs but the body […]

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Brain Fog and Cognitive Dysfunction in Lyme Disease

Brain Fog and Cognitive Dysfunction in Lyme Disease

Many patients with Lyme disease describe a frustrating and often frightening experience: they can no longer think the way they used to. Concentration is harder. Words feel just out of reach. Tasks that once felt automatic now require intense effort. This constellation of symptoms is commonly referred to as brain fog. While the term is

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7 Gut Clues Lyme Disease Might Be Involved

Lyme disease gut symptoms: 7 clues your doctor may miss

Lyme Disease Gut Symptoms: 7 Clues Your Doctor May Miss One family came to me after their 11-year-old daughter had been struggling with stomach aches, poor appetite, and nausea for months. She was missing school, and every GI test came back normal. The family had tried changing her diet, adding probiotics, and even therapy because

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Why Pediatric Lyme Screening Can’t Wait

Why Pediatric Lyme Screening Can’t Wait

Lyme screening is rarely part of routine medical care, even in regions where tick exposure is common. When early Lyme disease is not recognized, diagnosis and treatment are often delayed until symptoms become more complex and disruptive. In children, these delays can affect learning, behavior, and long-term health during critical stages of development. What NIH

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Why Constipation Is Common in Lyme Disease

Why Constipation Is Common in Lyme Disease

If your digestion has slowed and nothing seems to help, you’re not alone Constipation is a common and often frustrating symptom in people with Lyme disease. Some patients notice fewer bowel movements. Others experience hard stools, straining, bloating, or a constant sense of incomplete emptying despite adequate hydration and fiber. This symptom is common in

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Chronic Lyme vs PTLDS: The Debate

Chronic Lyme vs PTLDS: The Debate

The debate over chronic Lyme vs PTLDS isn’t just about words—it’s about whether patients feel validated or dismissed. Many patients use chronic Lyme disease to describe ongoing fatigue, pain, and brain fog. Some clinicians prefer post-treatment Lyme disease syndrome (PTLDS), a term that sounds more neutral but often feels minimizing. Did You Know? Most patients

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post-treatment Lyme disease syndrome (PTLDS)

Understanding Persistent Lyme Disease Symptoms

Post-Treatment Lyme Disease Syndrome (PTLDS) For many patients, Lyme disease does not end when treatment stops. Symptoms persist, evolve, or return — sometimes for months or years after antibiotics are completed. This is persistent Lyme disease. It is not rare, not imagined, and not fully explained by any single mechanism. It is what patients live

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Immune Dysregulation and Neuroinflammation in Lyme Disease

Immune Dysregulation in Lyme Disease

Many patients with Lyme disease experience persistent symptoms that are increasingly understood to involve immune dysregulation, even long after the initial infection has been treated. These symptoms are often misunderstood or minimized. Increasingly, they are recognized as reflecting immune dysregulation and neuroinflammation—a state in which immune signaling fails to return fully to baseline and continues

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When Vision Lingers: Understanding Palinopsia and Repeating Images

Palinopsia: Why Afterimages Won’t Go Away | Daniel Cameron MD

When Vision Doesn’t Let Go Some patients notice that an image disappears, but their vision does not fully reset. Lights may trail, words linger on the page, or objects seem to echo briefly in space. These experiences can be confusing and unsettling, particularly when they occur without warning. This phenomenon is known as palinopsia. Although

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