How to protect yourself from ticks with Permethrin-treated clothing


Several studies have found that wearing permethrin-treated clothing can reduce the risk of tick bites. But very few studies have looked at the behavior of a tick when it comes in contact with permethrin-treated clothing. Does it climb onto the insecticide-soaked textile or avoid it entirely? Does permethrin actually kill ticks?

As more individuals begin to venture outside with warmer weather, there are often concerns over how to protect yourself from ticks. Researchers have examined not only the effectiveness of various repellents and protective clothing but also the behavior of individuals who are more likely to encounter ticks.

Researchers in Indiana looked at the protective measures used by recreational hikers in their state. Surprisingly, they found that only 9.5% of hikers used a tick repellent, even fewer (3.4%) wore protective clothing and only 2 individuals “indicated that they took a shower post-recreation and used that activity to search for tick bites.” [1]

Ultrasonic device

Meanwhile, investigators in Australia recently studied the efficacy of ultrasonic pest repellent devices against the Australian paralysis tick, Ixodes holocyclus. “As more than 80% of the ticks were not repelled within the confined area, this level of repellency is clearly insufficient to provide adequate protection from a potential tick bite,” they conclude. [2]

Permethrin-treated clothing

Several studies have looked at Permethrin-treated clothing in repelling ticks.  Sullivan et al. recruited state and county park employees from North Carolina to wear long-lasting Permethrin-impregnated (LLPI) clothing. The authors found that the clothing “retained Permethrin and bioactivity against ticks after three months of use in real-world conditions.” [3]

A study in Rhode Island aimed to provide insight as to how to protect yourself from ticks by examining Permethrin-treated footwear. The authors found that people wearing sneakers and socks treated with Permethrin were 73.6 times less likely to have a tick bite than those wearing untreated footwear. [4]

Researchers found “people wearing sneakers and socks treated with Permethrin were 73.6 times less likely to have a tick bite than those wearing untreated footwear.”

Meanwhile, another study explored the behavior of ticks when they encounter Permethrin-treated clothing. How do ticks react? Using a model that mimicked a pant leg or the arm of a long-sleeved shirt, scientists studied the behavior and fate of ticks when exposed to Permethrin-treated clothing. [5]

“Ticks approaching a textile impregnated with a strong non-contact spatial repellent (DEET) very rarely made physical contact with the treated textile,” according to Eisen and colleagues from the Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases at the Centers for Disease Control and Prevention. [4]

Tick behavior when exposed to Permethrin

However, Permethrin-treated textiles did not repel ticks without contact, as seen with DEET. In fact, the majority (88%) of nymphal ticks chose to move onto Permethrin-treated textile versus DEET-treated textile.

After coming in contact with the treated clothing, the ticks dislodged through a “hot-foot” effect.

“Ticks readily walked onto a Permethrin-treated textile…. but laboratory-reared ticks became visibly agitated, displaying a hot-foot effect, and escaped contact with the Permethrin-treated textile by tumbling downwards until they dislodged themselves completely from a textile-covered assay card.”

Unfortunately, field-collected ticks were hardier than laboratory-reared ticks and able to sustain longer contact with the treated textile. The authors postulated that field-collected ticks have been exposed to highly variable temperatures and humidity conditions which may result in slower absorption of Permethrin.

“However, by 1 and 24 hours post-exposure very few ticks displayed normal movement, thus presenting minimal risk to bite, regardless of whether they were reared in the laboratory or collected in the field.”

“Contact with Permethrin-treated textiles negatively impacts the vigor and behavior of nymphal ticks for >24 hours,” according to Eisen, “with outcomes ranging from complete lack of movement to impaired movement and unwillingness of ticks displaying normal movement to ascend onto a human finger.”

One day after exposure, a majority of ticks were completely motionless. The remaining ticks were able to recover. “Ticks having recovered normal movement 1 day after exposure in our study most often ascended onto a finger when given the opportunity (and presumably also were capable of biting),” Eisen points out.

“In a real-life scenario, prolonged periods of time where ticks having fallen off a human host after contact with Permethrin-treated textile are unable to move will undoubtedly increase the risk of mortality due to desiccation or predation.”

“A scenario more difficult to address in a bioassay is when a tick makes initial contact with bare skin and subsequently approaches loose-fitting summer-weight Permethrin treated garments, such as shorts or a T-shirt,” states Eisen.

“In this case, the tick may walk underneath the treated textile and be contacted primarily from the dorsal side as the person moves and the clothing comes in and out of contact with the tick and the person’s skin.”

Permethrin is acutely toxic in high doses. The authors did not address the potential toxicity of Permethrin to humans. “Acute signs of toxicity to the central nervous system include incoordination, ataxia, hyperactivity, convulsions, and finally prostration, paralysis, and death,” according to a review by the National Research Council (US) Subcommittee to Review Permethrin Toxicity from Military Uniforms. [6]

Note: Users have been advised not to inhale Permethrin when treating clothes and not to apply Permethrin to the skin.

Article Updated: June 1, 2021

  1. Anderson KR, Blekking J, Omodior O. Tick trails: the role of online recreational trail reviews in identifying risk factors and behavioral recommendations associated with tick encounters in Indiana. BMC Public Health. 2021;21(1):908. Published 2021 May 13. doi:10.1186/s12889-021-10940-4
  2. Panthawong A, Doggett SL, Chareonviriyaphap T. The Efficacy of Ultrasonic Pest Repellent Devices against the Australian Paralysis Tick, Ixodes holocyclus (Acari: Ixodidae). Insects. 2021;12(5):400. Published 2021 Apr 30. doi:10.3390/insects12050400
  3. Sullivan KM, Poffley A, Funkhouser S, et al. Bioabsorption and effectiveness of long-lasting permethrin-treated uniforms over three months among North Carolina outdoor workers. Parasit Vectors. 2019;12(1):52. Published 2019 Jan 23. doi:10.1186/s13071-019-3314-1
  4. Tick Encounter.
  5. Eisen L, Rose D, Prose R, et al. Bioassays to evaluate non-contact spatial repellency, contact irritancy, and acute toxicity of permethrin-treated clothing against nymphal Ixodes scapularis ticks. Ticks Tick Borne Dis. 2017.
  6. Health Effects of Permethrin-Impregnated Army Battle-Dress Uniforms (1994) by National Research Council. 1994. Washington, DC: The National Academies Press. at Last accessed 8/12/17.

8 Replies to "How to protect yourself from ticks with Permethrin-treated clothing"

  • T Allen
    05/03/2022 (9:10 pm)

    Adult ticks can more amazingly fast. If they are hungry I’ve seen them run across permethrin treated clothing for 4-6″, towards skin, before I stopped them. You have to be covered head to toe with tight closures at wrists, ankles, and neck to stop them and then they’ll be on your head. The only guarantee of no tick bites is a hazmat suit so I recommend having the best known herbs for treating Lyme (Cat’s Claw, Otoba bark, Cystus incanus, cryptolepsis, Andrographis, etc) on hand and using one of them daily if the ground isn’t covered with snow and Cat’s Claw/Otoba for 10days after every bite. This has worked for myself and my dog for 5 years. My dog tested positive for Anaplasmosis but never had symptoms and I haven’t tested positive for Lyme despite getting bitten by ticks that have tested positive. Be safe!

  • James Katz MD
    05/20/2019 (1:06 pm)

    Permethrin is a derivative of oil of the chrysanthemum flower. The NRC statement on the toxicity of permethrin (1994) is woefully out of date. The EPA summary of evidence (2009 ) concludes when used as directed it is safe for children and pregnant mothers. All 5 major species of ticks in the US are disabled or dead within 30 seconds. Armies around the world using permethrin-treated uniforms and DEET have eliminated 99% of tick-borne diseases, including Lyme.

  • Lynn Sheridan
    05/16/2019 (7:13 pm)

    Avid Northern NH hiker here. We’ve been treating our clothing with permithrin for the past 2 years and have been very happy with the results. We also treat our dog with Vectra 3D which also contains permethrin and other chemicals. Also successful. Please be advised, it is extremely toxic to cats.

  • Colleen
    06/17/2018 (12:56 am)

    Permethrin kills ticks deet does not.
    Treat clothing with Permethrin and exposed skin with deet as a repellent.
    Studies show deet is still the best as a repellent, Picaridin second to deet and dies not soak into your skin as deet does.
    Picaridin can also be used in clothing.
    Better yet wear snug fitting treated clothing or with elastic bands to keep them from crawling up and under.
    Permethrin also looses it’s quality as days and washing pass especially if exposed to harsh sun.
    I’ve started asking party hosts if they have treated their property…
    If wearing a dress or skirt a snug pair of exercise short that have been treated under for some added protection, but the best is to do tick checks often. The longer they are in the more chance of contracting one of the tbd’s.So when you’re at a lawn party, do your tick check every time you use the rest room.
    Enjoy your summer!

  • Jill Padawer
    06/11/2018 (5:14 pm)

    Very helpful research article that clarifies how permethrin works. Given this, and that on the one hand permethrin kills ticks better than does Deet… given that the ticks can crawl up under the treated clothes, do you recommend Permethrin treated sneakers and clothes or DEET? And, for women (or men) needing to be in sandles or leather/synthetic material shoes while on the grass (e.g., outdoor parties), do you think Permethrin has any effect sprayed on a hard sole sandle, unlike the material of sneakers? Was faced with this dilemma this past weekend! A 6-hr lawn party… Yikes! Thank you!

    • Dr. Daniel Cameron
      06/12/2018 (12:29 pm)

      It took up to 10 seconds for the permethin impregnated cloth to cause the tick to drop off. The tick would appear to do well if it could contact skin in less than 10 seconds. It is also not clear if the permethrin protection would hold up after washing cloths. I am not convinced that ticks would stay on a sandals long enough to fall off when the skin is there.

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