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How to test for Lyme disease using a tick

It can be difficult to prove Lyme disease with serologic tests. So, doctors took an unusual approach with the first in-human study to identify the infection with Xenodiagnosis. Using this methodology, uninfected larval ticks fed on 23 study participants. Two of them tested positive for B. burgdorferi, the causative agent of Lyme disease. [1]