It has been 18 years since GlaxoSmithKlein pulled its preventative Lyme disease vaccine for humans, known as LYMErix, from the market. Now, a new vaccine is currently in Stage 2 clinical trials. This vaccine is also derived, in part, from the same OspA bacterial protein found in LYMErix. This begs the question: Will a new Lyme disease vaccine succeed or suffer the same fate as LYMErix?
When ticks are questing, they hold onto leaves, grass and other objects with their third and fourth pair of legs. They hold their front legs outstretched, waiting to climb onto the host as it passes by. But, when do ticks quest?
Patients with post-treatment Lyme disease syndrome (PTLDS) may experience sleep disturbances, according to a study by Johns Hopkins University School of Medicine. Researchers found, “PTLDS participants reported significantly worse global sleep and sleep disturbance scores and worse fatigue, functional impact, and more cognitive-affective depressive symptoms compared to poor-sleeping controls.” 
I have found that in my practice, Lyme disease in children can cause emotional, educational, and social issues, oftentimes with debilitating consequences. Some of the parents have felt overwhelmed by their child’s illness. Could there be parental flooding during conflicts with a child who has Lyme disease?
Although studies indicate that most infections have a similar effect on pregnant vs. non-pregnant women, several (such as influenza, hepatitis E, herpes simplex virus infections, malaria) may be more severe in pregnant women. Now, researchers investigate whether Borrelia burgdorferi bacteria, the pathogen causing Lyme disease, might impact pregnancy outcome, as well.
There are ticks in them thar hills. It appears that ticks are everywhere, even in the Alps. In the late 1980’s, ticks did not exist or were rare in Italy’s Piedmont region, located at the base of the Alps. But, “In recent years, a marked increase in tick abundance has been observed in several Alpine valleys, together with more frequent reports of Lyme borreliosis,” writes Garcia-Vozmediano and colleagues. 
A study by Tulloch and colleagues, published in the journal BJGP Open, examined the decision-making behavior of general practitioners (GPs) when applying Read codes to non-specific clinical presentations. The authors used Lyme disease as a case example and recruited GPs in the North West of England. 
A recent article, published in the journal Clinical Case Reports, describes the case of a 62-year-old man, from Norway, who was initially diagnosed with shingles, a viral infection which produces a painful skin rash with blisters in a localized area on the body.  Shingles, also known as herpes zoster, is common in older individuals who have had chickenpox.
Clinicians from Mayo Clinic describe 6 cases of neurological Lyme disease in the journal Open Forum Infectious Diseases.  Five of the cases presented with Bannwarth syndrome (BWS), an uncommon manifestation of neurologic Lyme disease.
There have been reports of Borrelia burgdorferi (Bb), the bacterial agent of Lyme disease, triggering primary dementia, such as Alzheimer’s disease. Researchers who examined the records of 1,594 patients with dementia found that 1.25% had a positive intrathecal anti-Borrelia antibody index (AI), specific for neuroborreliosis. They concluded, “Pure Lyme dementia exists and has a good outcome after antibiotics.” 1
Dr. Daniel Cameron, MD, MPH, is a nationally recognized leader for his expertise in the diagnosis and treatment of Lyme disease and other tick-borne illnesses. For more than 30 years, he has been treating adolescents and adults suffering from Lyme disease.