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Lyme Science Blog

PTLDS Ethical Challenges Deserve Attention

The Ethical Cost of Dismissing PTLDS

The ethical challenges of post-treatment Lyme disease syndrome (PTLDS) often begin at the moment symptoms persist after treatment. Patients may do everything right—receive a timely diagnosis, complete recommended antibiotics, and follow medical advice—yet continue to worsen. This is not simply a clinical dilemma. It is an ethical one. Why This Matters Clinically These ethical challenges […]

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Gastrointestinal Dysregulation in Lyme Disease

Gastrointestinal Dysregulation in Lyme Disease

If your digestion has slowed and nothing seems to help, you’re not alone. Many patients with Lyme disease develop gastrointestinal symptoms that persist despite dietary changes, fiber supplementation, hydration, or normal testing. These symptoms may include constipation, bloating, early satiety, nausea, abdominal discomfort, or a constant sense that digestion is not moving forward properly. In

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Understanding Central Sensitization in Lyme Disease

Pain Processing and Central Sensitization in Lyme Disease

When Pain Persists Beyond Infection Some patients with Lyme disease experience pain that spreads, fluctuates, or intensifies long after the acute infection has been treated. Symptoms may worsen with stress, sleep disruption, or physical exertion and often seem disproportionate to findings on examination or testing. When conventional explanations fall short, it becomes necessary to consider

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Why Patients With Lyme Disease Feel Exhausted Despite Sleeping

Why Patients With Lyme Disease Feel Exhausted Despite Sleeping

Patients with Lyme disease sleep disorders often describe the same experience: they sleep through the night yet wake feeling depleted. This is not about sleep duration—it is about biologic fatigue and impaired recovery. Many patients with Lyme disease experience what clinicians describe as non-restorative sleep, a state in which sleep occurs but the body does

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Brain Fog and Cognitive Dysfunction in Lyme Disease

Brain Fog and Cognitive Dysfunction in Lyme Disease

Many patients with Lyme disease describe a frustrating and often frightening experience: they can no longer think the way they used to. Concentration is harder. Words feel just out of reach. Tasks that once felt automatic now require intense effort. This constellation of symptoms is commonly referred to as brain fog. While the term is

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Why Pediatric Lyme Screening Can’t Wait

Why Pediatric Lyme Screening Can’t Wait

Lyme screening is rarely part of routine medical care, even in regions where tick exposure is common. When early Lyme disease is not recognized, diagnosis and treatment are often delayed until symptoms become more complex and disruptive. In children, these delays can affect learning, behavior, and long-term health during critical stages of development. For a

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Why Constipation Is Common in Lyme Disease

Why Constipation Is Common in Lyme Disease

If your digestion has slowed and nothing seems to help, you’re not alone Constipation is a common and often frustrating symptom in people with Lyme disease. Some patients notice fewer bowel movements. Others experience hard stools, straining, bloating, or a constant sense of incomplete emptying despite adequate hydration and fiber. This symptom is common in

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Chronic Lyme vs PTLDS: The Debate

Chronic Lyme vs PTLDS: The Debate

The debate over chronic Lyme vs PTLDS isn’t just about words—it’s about whether patients feel validated or dismissed. Many patients use chronic Lyme disease to describe ongoing fatigue, pain, and brain fog. Some clinicians prefer post-treatment Lyme disease syndrome (PTLDS), a term that sounds more neutral but often feels minimizing. Did You Know? Most patients

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