Lyme Science Blog

Why One-Size-Fits-All Lyme Treatment Fails Many Patients Standard treatment works for some Others remain ill after therapy Symptoms reflect different mechanisms Care must be individualized One-size-fits-all Lyme treatment fails too many patients. While standard antibiotic courses work for some, others remain ill with fatigue, brain fog, joint pain, and autonomic dysfunction long after treatment ends. […]

Lyme Disease Symptoms: Why They Come and Go (A Complete Guide) Lyme disease symptoms often don’t follow a predictable pattern—and that’s where many patients are misunderstood. Fatigue, joint pain, neurologic symptoms, and cognitive changes may come and go, making diagnosis difficult. Key Question: What symptoms suggest Lyme disease—and why are they often overlooked? This question

Why Lyme Disease Is Not Getting Better: Breaking the Groundhog Day Cycle Every day can feel the same with chronic illness. Symptoms repeat without clear answers. Progress feels stalled despite ongoing care. Many patients with Lyme disease describe their experience the same way: every day feels like Groundhog Day. They wake up with the same

When Lyme Disease Treatment Guidelines Don’t Work: PTLDS and Clinical Decisions What happens when Lyme disease guidelines don’t fit? How should clinicians approach persistent symptoms? Ethics and uncertainty shape real-world decisions. Lyme disease treatment guidelines provide structure for care, but post-treatment Lyme disease syndrome (PTLDS) guidelines do not always account for every clinical scenario. When

Lyme Disease Co-infections: What You Need to Know Lyme disease co-infections occur when a single tick bite transmits multiple pathogens. Up to 40% of Lyme patients in some regions also carry Babesia, Bartonella, Anaplasmosis, or Ehrlichia—yet these infections are frequently missed. When co-infections go unrecognized, patients don’t fully recover. Standard Lyme treatment won’t clear a

Borrelia miyamotoi: What You Need to Know Borrelia miyamotoi is a tick-borne bacterium that causes relapsing fever. It is transmitted by the same ticks that spread Lyme disease but can cause different symptoms. Unlike Lyme disease, Borrelia miyamotoi does not typically cause a bull’s-eye rash. Understanding Borrelia miyamotoi – What is Borrelia miyamotoi? – What

Powassan Virus: What You Need to Know Powassan virus is a rare but serious tick-borne illness that can cause inflammation of the brain (encephalitis) and the membranes surrounding the brain and spinal cord (meningitis). Unlike Lyme disease, Powassan virus can be transmitted within minutes of a tick bite. For an overview, see Powassan virus. Understanding

When Lyme Disease Is Missed: A Case from My Practice A Lyme disease missed diagnosis often begins quietly—when key diagnoses are never considered. Just a couple of weeks ago, I had a new patient on my schedule—someone who specifically requested a consultation for Lyme disease. Before the visit, I reviewed her chart, expecting to see

Lyme Disease Loneliness: Why Patients Feel Isolated “No one really understands.” Many Lyme patients feel this. Loneliness can become part of the illness. Lyme disease loneliness can be one of the most difficult parts of living with chronic illness. One patient once said, “No one really understands what this feels like.” That quiet sentence reflects