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Lyme Science Blog

Why Morning Stiffness Improves During the Day

Why Morning Stiffness Improves During the Day

Why Morning Stiffness Improves During the Day If you wake up stiff every morning but feel better as the day goes on, you’re not imagining it. Morning stiffness that improves with movement is a common and meaningful symptom pattern—and it offers an important clinical clue. Many patients describe the same daily experience. They wake up […]

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Sciatic Pain or SI Joint Dysfunction? A Common Diagnostic Trap

Sciatic Pain vs SI Joint Dysfunction in Lyme Disease

Sciatic Pain vs SI Joint Dysfunction in Lyme Disease Sciatic pain vs SI joint dysfunction is one of the most frequent—and most challenging—comparisons in patients with low back, buttock, and leg pain. Many patients are told they have sciatica simply because pain travels into the leg. But pain location alone does not define the diagnosis.

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delaying pediatric Lyme treatment

When Fear Delays Pediatric Lyme Treatment: A Year Lost to Lyme Disease

When Fear Delays Pediatric Lyme Treatment: A Year Lost to Lyme Disease When this family brought their son to me, they were facing a decision many parents encounter when delaying pediatric Lyme treatment—whether fear of antibiotics might outweigh the risk of waiting. They were not opposed to treating Lyme disease. But fear stood in the

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What People Mean by “End-Stage” Lyme Disease

What People Mean by “End-Stage” Lyme Disease Patients sometimes come to my office using the phrase “end-stage Lyme disease.” It is a powerful term, and it reflects how profoundly ill they feel. However, late-stage Lyme disease is not a formal medical diagnosis. Most often, patients are using this language to describe severe, persistent illness consistent

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Is This Lyme Disease or Something Else?

Alpha-Gal Syndrome: Tick-Borne Red Meat Allergy

What Is Alpha-gal Syndrome? Alpha-gal red meat allergy is a tick-borne food allergy that can cause serious reactions to mammalian meat. Many patients diagnosed with this condition immediately worry they have developed another chronic illness. That fear is understandable—especially for individuals with a history of tick exposure or Lyme disease. But when managed correctly, alpha-gal

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Shania Twain and Lyme Disease: When a Tick Bite Affected Her Voice

Shania Twain and Lyme Disease: When a Tick Bite Affected Her Voice Quick Answer: Shania Twain developed neurologic complications from Lyme disease that affected her vocal cords, leading to dysphonia. Her case highlights how Lyme disease can impact the nervous system in rare and unexpected ways. Shania Twain, the global country-pop icon known for hits

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PTLDS Ethical Challenges Deserve Attention

The Ethical Cost of Dismissing PTLDS

The Ethical Cost of Dismissing PTLDS The ethical challenges of post-treatment Lyme disease syndrome (PTLDS) often begin at the moment symptoms persist after treatment. Patients may do everything right—receive a timely diagnosis, complete recommended antibiotics, and follow medical advice—yet continue to worsen. This is not simply a clinical dilemma. It is an ethical one. Why

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Gastrointestinal Dysregulation in Lyme Disease

Gastrointestinal Dysregulation in Lyme Disease

Gastrointestinal Dysregulation in Lyme Disease If your digestion has slowed and nothing seems to help, you’re not alone. Many patients with Lyme disease develop gastrointestinal symptoms that persist despite dietary changes, fiber supplementation, hydration, or normal testing. These symptoms may include constipation, bloating, early satiety, nausea, abdominal discomfort, or a constant sense that digestion is

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Understanding Central Sensitization in Lyme Disease

Pain Processing and Central Sensitization in Lyme Disease

Pain Processing and Central Sensitization in Lyme Disease When Pain Persists Beyond Infection Some patients with Lyme disease experience pain that spreads, fluctuates, or intensifies long after the acute infection has been treated. Symptoms may worsen with stress, sleep disruption, or physical exertion and often seem disproportionate to findings on examination or testing. When conventional

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Why Patients With Lyme Disease Feel Exhausted Despite Sleeping

Why Patients With Lyme Disease Feel Exhausted Despite Sleeping

Why Patients With Lyme Disease Feel Exhausted Despite Sleeping Patients with Lyme disease sleep disorders often describe the same experience: they sleep through the night yet wake feeling depleted. This is not about sleep duration—it is about biologic fatigue and impaired recovery. Many patients with Lyme disease experience what clinicians describe as non-restorative sleep, a

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