Lyme Science Blog

Gastrointestinal Dysregulation in Lyme Disease If your digestion has slowed and nothing seems to help, you’re not alone. Many patients with Lyme disease develop gastrointestinal symptoms that persist despite dietary changes, fiber supplementation, hydration, or normal testing. These symptoms may include constipation, bloating, early satiety, nausea, abdominal discomfort, or a constant sense that digestion is […]

Pain Processing and Central Sensitization in Lyme Disease When Pain Persists Beyond Infection Some patients with Lyme disease experience pain that spreads, fluctuates, or intensifies long after the acute infection has been treated. Symptoms may worsen with stress, sleep disruption, or physical exertion and often seem disproportionate to findings on examination or testing. When conventional

Why Patients With Lyme Disease Feel Exhausted Despite Sleeping Patients with Lyme disease sleep disorders often describe the same experience: they sleep through the night yet wake feeling depleted. This is not about sleep duration—it is about biologic fatigue and impaired recovery. Many patients with Lyme disease experience what clinicians describe as non-restorative sleep, a

Brain Fog and Cognitive Dysfunction in Lyme Disease Many patients with Lyme disease describe a frustrating and often frightening experience: they can no longer think the way they used to. Concentration is harder. Words feel just out of reach. Tasks that once felt automatic now require intense effort. This constellation of symptoms is commonly referred

7 Gut Clues Lyme Disease Might Be Involved A family’s 11-year-old daughter had been struggling with stomach aches, poor appetite, and nausea for months. She was missing school, and every GI test came back normal. The family had tried changing her diet, adding probiotics, and even therapy because they were told it might just be

The Early Warning Signs of a Lyme Flare That Patients Know Before It Hits You’re not “sick” yet.But your body knows.You feel the shift — before the symptoms have a name. It might start with a flash of irritability.Or a strange sense of clarity that doesn’t match your day.Then the fatigue rolls in. And you

Why Constipation Is Common in Lyme Disease Quick Answer: Constipation in Lyme disease is often caused by autonomic nervous system dysfunction slowing gut motility—even when diet, hydration, and routine tests appear normal. Clinical Insight: Constipation in Lyme disease often reflects autonomic nervous system dysfunction rather than diet, hydration, or routine gastrointestinal causes. If your digestion

Chronic Lyme vs PTLDS: The Debate The debate over chronic Lyme vs PTLDS isn’t just about words—it’s about whether patients feel validated or dismissed. Many patients use chronic Lyme disease to describe ongoing fatigue, pain, and brain fog. Some clinicians prefer post-treatment Lyme disease syndrome (PTLDS), a term that sounds more neutral but often feels