Lyme Science Blog

Why Constipation Is Common in Lyme Disease Quick Answer: Constipation in Lyme disease is often caused by autonomic nervous system dysfunction slowing gut motility—even when diet, hydration, and routine tests appear normal. Clinical Insight: Constipation in Lyme disease often reflects autonomic nervous system dysfunction rather than diet, hydration, or routine gastrointestinal causes. If your digestion […]

Chronic Lyme vs PTLDS: The Debate The debate over chronic Lyme vs PTLDS isn’t just about words—it’s about whether patients feel validated or dismissed. Many patients use chronic Lyme disease to describe ongoing fatigue, pain, and brain fog. Some clinicians prefer post-treatment Lyme disease syndrome (PTLDS), a term that sounds more neutral but often feels

Immune Dysfunction and Dysregulation in Lyme Disease Immune dysregulation in Lyme disease may help explain why symptoms such as fatigue, pain, and cognitive changes can persist—even when standard tests are normal and initial treatment has been completed. Many patients with Lyme disease experience persistent symptoms that are increasingly understood to involve immune dysregulation, even long

When Medicine Says There’s Nothing More to Do When symptoms persist beyond what medicine can easily explain Author’s note: I wrote this because I often meet patients who have been told there is nothing more to do, even though their symptoms persist. This post explains why that phrase usually reflects the limits of a medical

When Symptoms Are Blamed on Aging, Look Deeper When Symptoms Are Blamed on Aging Symptoms blamed on aging are often accepted without question. A patient noticed a gradual decline in stamina as routine activities became exhausting, sleep no longer felt restorative, and shortness of breath appeared with simple tasks. He assumed it was just getting

Long COVID or Lyme Disease? When Symptoms Don’t Add Up He wasn’t losing his mind—he was losing time. Each week blurred into the next as fatigue and fog deepened. When he finally came to my office, he’d already accepted a diagnosis that wasn’t quite right. A patient came to me months after recovering from COVID-19.