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Lyme Science Blog

Why I Treated Him for Lyme Even When His Test Was Negative

Why I Treated Him for Lyme—Even When His Test Was Negative

Patients Deserve an Explanation This article is part of an ongoing series addressing persistent myths about Lyme disease. One of the most common—and most important—questions I hear from patients is: “If my Lyme test is negative, why are you still treating me?” It’s a fair question. And if you’re asking it, you deserve a clear […]

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Unexpected Relief from Allodynia: Lyme Disease Treatment Worked!

Allodynia is a neurological condition where non-painful stimuli—like a breeze, the pressure of clothing, or even light touch—cause pain. It’s often associated with central sensitization, where the brain and spinal cord become overly responsive to nerve signals. But sometimes, the trigger is more than just misfiring nerves. Sometimes, it’s caused by an infection, such as

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Could Piperacillin Be the Lyme Breakthrough We Need?

Could Piperacillin Be the Lyme Disease Breakthrough We Need?

A recent study published in Science Translational Medicine by researchers at Northwestern University has generated cautious optimism in the Lyme disease community. The study found that an older antibiotic—piperacillin—was able to clear Borrelia burgdorferi, the bacteria that causes Lyme disease, in mice at doses 100 times lower than doxycycline. This is noteworthy. Doxycycline has long

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Can Lyme disease stay hidden during pregnancy and only emerge after childbirth?

A 23-year-old woman from Brooklyn, NY, presented to her primary care physician with bilateral knee swelling and pain three days after delivering a healthy baby girl. She rated the pain as 8 out of 10 in severity and reported that it worsened with walking. Case The patient recalled experiencing similar knee pain for two days

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Could Lyme Disease Be Wrecking Your Gut Without You Knowing It?

Have you ever felt like your gut was in chaos—like nothing you eat sits right, no doctor can find a clear cause, and your symptoms don’t seem to make sense? You’re not alone. I’ve had many patients tell me they’ve tried everything—probiotics, elimination diets, GI scopes—only to come back with normal labs and no answers.

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Babesia Blood Transfusion: How One Unit Changed Everything

Babesia blood transfusion transmission is more common than most people realize. When we think of tick-borne illnesses like Babesia, we often picture outdoor exposure in wooded, high-risk areas. But what happens when Babesia shows up in someone who hasn’t been outdoors—and hasn’t been bitten by a tick? One recent case reminds us that Babesia can

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