Lyme Science Blog

Immune Dysregulation in Lyme Disease: Why Symptoms Persist Immune dysregulation in Lyme disease may help explain why symptoms such as fatigue, pain, and cognitive changes can persist—even when tests are normal and initial treatment has been completed. Many patients improve—but do not return fully to baseline. This page explains why. Clinical Insight: Persistent symptoms in

When Medicine Says There’s Nothing More to Do “NOTHING MORE CAN BE DONE?” WHEN SYMPTOMS STILL PERSIST What does it really mean when you’re told there is nothing more to do—yet your symptoms continue? Author’s note: I wrote this because I often meet patients who have been told there is nothing more to do, even

When Symptoms Are Blamed on Aging, Look Deeper When Symptoms Are Blamed on Aging Symptoms blamed on aging are often accepted without question. A patient noticed a gradual decline in stamina as routine activities became exhausting, sleep no longer felt restorative, and shortness of breath appeared with simple tasks. He assumed it was just getting

Long COVID or Lyme Disease? When Symptoms Don’t Add Up He wasn’t losing his mind—he was losing time. Each week blurred into the next as fatigue and fog deepened. When he finally came to my office, he’d already accepted a diagnosis that wasn’t quite right. A patient came to me months after recovering from COVID-19.

Fear of a Herxheimer: Why Delaying Treatment Backfires Fear of a Herxheimer reaction is one of the most common reasons patients delay Lyme treatment. The worry can feel bigger than the disease itself. I remember one patient sitting across from me, struggling to find the words before finally admitting: “I’m scared to treat my Lyme