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Lyme Science Blog

Which Lyme disease guidelines should you follow for Lyme Carditis?

In their  article Lyme Carditis: A Rare Presentation of Sinus Bradycardia Without Any Conduction Defects, Grella and colleagues present “a unique case of Lyme carditis, without the classical findings of Lyme disease [such as a rash] or common EKG findings of AV conduction abnormalities.”¹ The case highlights the differences in Lyme disease guidelines. A 56–year-old […]

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Girl in a wheelchair

Psychiatric lyme disease

In their article, Bransfield et al. describe two patients with complex, multisystemic illnesses, which included Lyme disease. Both patients suffered from debilitating symptoms over several years, leaving them unable to walk and confined to a wheelchair. Doctors dismissed their complaints, which ranged from fatigue and weight loss to seizures and cognitive impairments. They were labeled

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Conversion disorder, Guillain-Barré syndrome or neurologic Lyme disease?

Teodoro and colleagues describe the case of a woman who was initially suspected of having a conversion disorder but later diagnosed with Guillain-Barré syndrome, possibly triggered by neurologic Lyme disease. ¹ (Conversion disorder is a mental condition in which a person has blindness, paralysis, or other nervous system (neurologic) symptoms that cannot be explained by

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Babesia infection, transfusion

A severe Babesia infection

Although the majority of Babesia cases are treated with antimicrobial agents, patients with severe cases may require an exchange transfusion (ET). In their article, “Repeat exchange transfusion for treatment of severe babesiosis,” Radcliffe and colleagues describe the case of a 73-year-old woman with an extreme case of a Babesia infection, who was immunocompromised. [3] The woman ultimately

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Woman taking antibiotic pills

Is prolonged antibiotics treatment for Lyme disease the new norm?

According to an annual, cross-sectional, nationwide survey, 20.3% were treated for 5 to 8 weeks, while 35.6% were treated for more than 8 weeks. The CDC authors were surprised at the number of Lyme disease (LD) cases being treatment with long term antibiotics “A surprisingly large proportion of respondents reported receiving more than 8 weeks

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Tick-borne encephalitis and Lyme disease can lead to chronic illness

In an effort to better understand the role of the immune responses in the clinical course and post-treatment outcome of tick-borne encephalitis (TBE), Bogovič  and colleagues “assessed 24 cytokines and chemokines associated with innate and adaptive (T and B cell) immune responses.” A black-legged (Ixodes spp) tick can transmit tick-borne encephalitis and Lyme disease. The

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Fatal case of Neuroborreliosis

Neuroborreliosis manifestations typically include headaches and symptoms of meningitis, encephalopathy and stroke-like symptoms. The diagnosis is based on clinical symptoms and lumbar puncture findings. The woman had other serious health problems, which included lupus, a left-posterior parietal ventriculoperitoneal (VP) shunt due to congenital hydrocephalus, and migraine headaches, explains Khan. Diagnostic tests revealed renal failure and

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Lyme carditis diagnosis – 18 cases.

“[Lyme carditis] is caused by direct invasion of myocardial tissue by spirochetes and an immunological host response causing lymphocyte inflammation,” writes Marcos¹ in a discussion of Lyme carditis diagnosis.  Furthermore, “B. burgdorferi has a predisposition to cause inflammation of the atrioventricular (AV) node resulting in variable conduction abnormalities.” The 18 patients with possible Lyme carditis were

Lyme carditis diagnosis – 18 cases. Read More »