The US Food and Drug Administration (FDA) is pushing to regulate (or eliminate altogether) laboratory developed tests (LDT).  Diagnostic tests for Lyme disease will be targeted, initially, as the FDA begins to phase in its oversight.
A read of the Infectious Diseases Society of America (IDSA) 2006 evidence-based guidelines would lead you to believe that for Lyme disease one size fits all. All you need is a single 200 mg dose of doxycycline for a tick bite; a single 10 to 21 days of antibiotics for Lyme disease; but no retreatment.
President Barack Obama signed an Executive Order on Thursday, September 18th which creates a task force to address concerns over the spread of drug-resistant bacteria due to an overuse of antibiotics.
ILADS evidence base treatment guidelines identified two-failed treatment protocols, a single 200 mg dose of doxycycline and a single 10 to 21 day course of antibiotic using a GRADE assessment. ILADS evidence based treatment guideline published recommendations to improve these two-failed treatment protocols.