Lyme Science Blog

Immune Dysregulation in Lyme Disease Many patients with Lyme disease experience persistent symptoms that are increasingly understood to involve immune dysregulation, even long after the initial infection has been treated. These symptoms are often misunderstood or minimized. Increasingly, they are recognized as reflecting immune dysregulation and neuroinflammation—a state in which immune signaling fails to return […]

When Medicine Says There’s Nothing More to Do When symptoms persist beyond what medicine can easily explain Author’s note: I wrote this because I often meet patients who have been told there is nothing more to do, even though their symptoms persist. This post explains why that phrase usually reflects the limits of a medical

When Symptoms Are Blamed on Aging, Look Deeper When Symptoms Are Blamed on Aging Symptoms blamed on aging are often accepted without question. A patient noticed a gradual decline in stamina as routine activities became exhausting, sleep no longer felt restorative, and shortness of breath appeared with simple tasks. He assumed it was just getting

Long COVID or Lyme Disease? When Symptoms Don’t Add Up He wasn’t losing his mind—he was losing time. Each week blurred into the next as fatigue and fog deepened. When he finally came to my office, he’d already accepted a diagnosis that wasn’t quite right. A patient came to me months after recovering from COVID-19.

Fear of a Herxheimer: Why Delaying Treatment Backfires Fear of a Herxheimer reaction is one of the most common reasons patients delay Lyme treatment. The worry can feel bigger than the disease itself. I remember one patient sitting across from me, struggling to find the words before finally admitting: “I’m scared to treat my Lyme