Lyme Science Blog

Lyme Disease Gut Problems: Gastrointestinal Dysregulation and Motility Issues Many patients with Lyme disease develop gastrointestinal symptoms that persist despite dietary changes, fiber supplementation, hydration, or normal testing. Symptoms may include constipation, bloating, early satiety, nausea, abdominal discomfort, or a constant sense that digestion is not moving forward properly. In Lyme disease, these symptoms most […]

Central Sensitization in Lyme Disease: Why Pain Persists Pain that spreads, shifts, or worsens over time may not reflect ongoing infection—it may reflect how the nervous system is processing pain. Central sensitization in Lyme disease can explain why some patients continue to experience pain long after treatment. The pain may move, intensify, or feel out

Why Am I Exhausted After Sleeping? Lyme Disease and Non-Restorative Sleep Quick Answer: Many patients with Lyme disease feel exhausted even after a full night’s sleep because sleep is not fully restorative. Autonomic dysfunction, inflammation, and disrupted sleep architecture can prevent overnight recovery. Clinical Insight: When patients wake unrefreshed despite adequate sleep duration, the issue

Brain Fog and Cognitive Dysfunction in Lyme Disease: Symptoms and Causes Many patients with Lyme disease describe a frustrating and often frightening experience: they can no longer think the way they used to. Brain fog in Lyme disease reflects slowed thinking, poor concentration, and memory problems driven by neurologic and inflammatory changes. Concentration becomes harder.

7 Gut Clues Lyme Disease Might Be Involved Stomach pain. Nausea. Bloating. Sometimes the gut is one of the first systems affected. Normal GI tests do not always mean normal function. An 11-year-old girl had been struggling with stomach aches, poor appetite, and nausea for months. She was missing school, and every gastrointestinal test came

  Early Warning Signs of a Lyme Flare: Symptoms Patients Notice First YOU FEEL IT BEFORE IT HITS? EARLY SIGNS OF A LYME FLARE The early warning signs of a Lyme flare often begin before a full crash. Patients may notice subtle mood changes, strange fatigue, sensory overload, digestive changes, or a sudden sense that

Constipation in Lyme Disease: Why Gut Motility Slows CONSTIPATION THAT WON’T RESPOND? NORMAL TESTS BUT PERSISTENT SYMPTOMS? COULD THIS BE LYME-RELATED DYSFUNCTION? Constipation in Lyme disease is common and often misunderstood—especially when diet, hydration, and routine testing appear normal. “I was doing everything right—but nothing was working.” Quick Answer: Constipation in Lyme disease is often

Chronic Lyme vs PTLDS: What’s the Difference and Why It Matters The chronic Lyme vs PTLDS debate is not just about terminology — it is about whether patients feel validated or dismissed. Many patients use chronic Lyme disease to describe ongoing fatigue, pain, and brain fog that PTLDS does not fully capture. The language clinicians