Lyme Science Blog

Allodynia is a neurological condition where non-painful stimuli—like a breeze, the pressure of clothing, or even light touch—cause pain. It’s often associated with central sensitization, where the brain and spinal cord become overly responsive to nerve signals. But sometimes, the trigger is more than just misfiring nerves. Sometimes, it’s caused by an infection such as […]

A recent study published in Science Translational Medicine by researchers at Northwestern University has generated cautious optimism in the Lyme disease community. The study found that an older antibiotic—piperacillin—was able to clear Borrelia burgdorferi, the bacteria that causes Lyme disease, in mice at doses 100 times lower than doxycycline. This is noteworthy. Doxycycline has long

A 23-year-old woman from Brooklyn, NY, presented to her primary care physician with bilateral knee swelling and pain three days after delivering a healthy baby girl. She rated the pain as 8 out of 10 in severity and reported that it worsened with walking. Case The patient recalled experiencing similar knee pain for two days

It’s a warm day, you’ve been hiking, gardening, or walking the dog—and later that evening, you find a tick. Sound familiar? Ticks are stealthy, patient, and highly sensitive hunters. While they can’t jump or fly, they are remarkably good at detecting hosts from a distance. Whether you’re deep in the woods or lounging in your

After 37 years treating Lyme disease, I’ve seen psychiatric misdiagnosis delay treatment for years. A woman came to my office after seeing three different doctors. Each time, she heard the same thing: “You’re probably just depressed.” But her symptoms told a different story—one that pointed to Lyme disease, not mental illness. When the Diagnosis Doesn’t

Have you ever felt like your gut was in chaos—like nothing you eat sits right, no doctor can find a clear cause, and your symptoms don’t seem to make sense? You’re not alone. I’ve had many patients tell me they’ve tried everything—probiotics, elimination diets, GI scopes—only to come back with normal labs and no answers.

A Tale of Three Outcomes “I thought I was better… until I wasn’t.” That’s what one of my patients told me after completing a standard course of antibiotics for Lyme disease. At first, she felt relief—less pain, more energy. But weeks later, the fatigue crept back in. Then the brain fog. Then the joint pain

A Closer Look at Nature’s Most Unwelcome Parasites They’re small, stealthy, and surprisingly dangerous. Ticks have long held a place among the most loathed creatures in the natural world—and not without reason. While they may appear harmless at first glance, these tiny arachnids are capable of causing serious harm to both humans and animals. In

In a letter to the editor published in the Annals of Indian Academy of Neurology, Varma SY and colleagues¹ describe a rare and clinically significant case of Guillain-Barré Syndrome (GBS) triggered by Lyme disease in a 50-year-old woman. This case highlights the complex interplay between infectious diseases and autoimmune disorders. Initial Presentation and Symptoms The