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Lyme Science Blog

Rare Skin Manifestation of Lyme Disease in a Child

Rare Skin Manifestation of Lyme Disease in a Child A 6-year-old girl developed an unusual skin presentation of Lyme disease—highlighting how early infection can be missed when symptoms fall outside typical patterns. The child initially presented with an erythema migrans (EM) rash, followed weeks later by an areolar lymphocytoma involving her breast. She had recently

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Lyme misdiagnosis in children

Lyme Disease Misdiagnosis in Children: ED Study

Study Shows Doctors Can Misdiagnose Lyme Disease in Children Pediatric Lyme misdiagnosis remains a challenge, particularly in emergency departments where clinicians must make decisions before classic signs or positive tests appear. The CDC notes that Lyme disease can present with a wide range of symptoms, which can make early diagnosis difficult—especially in children. Emergency Department

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SINGLE DOSE DOXYCYCLINE

Single Dose Doxycycline for Lyme Disease: A Case With Poor Outcome

Single Dose Doxycycline for Lyme Disease: Why It May Not Be Enough Quick Answer: A single dose of doxycycline is sometimes used for prevention after a tick bite—but it is not a treatment for established Lyme disease. Clinical Insight: When early Lyme symptoms are present, a single dose may be insufficient and can allow the

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Back to the Ice Age

Lyme Disease Bacteria Dates Back to the Ice Age

Lyme Disease Bacteria Dates Back to the Ice Age Lyme disease may feel like a modern epidemic—but the bacteria behind it is not new. In an effort to understand the evolutionary history of Borrelia burgdorferi, Walter and colleagues at Yale University analyzed one of the largest collections of bacterial genomes assembled to date, using ticks

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Delayed Lyme Disease Treatment Leads to Carditis and Vision Loss

Delayed Lyme Disease Treatment Leads to Carditis and Vision Loss Lyme disease can progress quickly when early symptoms are overlooked or ignored. A 66-year-old man became ill within one week of a tick bite to the back of his neck. One month later, he collapsed and lost consciousness, according to Sharma and colleagues in The

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Using Dogs to Track Lyme Disease Risk in West Virginia

Using Dogs to Track Lyme Disease Risk in West Virginia Dogs may provide an early warning system for Lyme disease risk in humans. Researchers have long used animal sentinel studies to monitor the spread of Lyme disease. Domestic dogs are particularly useful because of their frequent outdoor exposure, known travel history, and ability to develop

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How Borrelia Evades the Immune System

How Borrelia Evades the Immune System Borrelia burgdorferi, the bacterium responsible for Lyme disease, has developed strategies that allow it to persist in the body despite immune responses and standard treatment. To better understand this process, Embers and colleagues studied infection in rhesus macaques—an animal model that closely reflects human Lyme disease. A Model That

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Lyme Disease Fatigue: Persistent Exhaustion and Pain After Treatment

Lyme Disease Fatigue: Persistent Exhaustion and Pain After Treatment EXHAUSTED EVEN AFTER REST? COULD THIS BE LYME DISEASE FATIGUE? Lyme disease fatigue is more than feeling tired. Patients often describe a deep, persistent exhaustion that does not improve with rest—and may worsen after even minor activity. For some, fatigue begins early during infection. For others,

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