Lyme Science Blog

In their article “Supportive Oligonucleotide Therapy (SOT) as a Potential Treatment for Viral Infections and Lyme Disease: Preliminary Results,” Apostolou and colleagues describe findings from a study aimed to evaluate the efficacy of SOT in 115 patients with either Epstein–Barr (EBV), Herpes Simplex Virus or Lyme Disease.¹ Oligonucleotide was administered intravenously to the participants and […]

In their study, “Impacts Over Time of Neighborhood-Scale Interventions to Control Ticks and Tick-Borne Disease Incidence,” Ostfeld and colleagues examined the effectiveness of tick control methods in 24 residential neighborhoods endemic for Lyme disease in New York.¹ The study, conducted over several years, assessed the impact of tick control system (TCS) bait boxes and Met52

However, the authors of a new case report suggest that for some Lyme carditis patients, placement of a temporary permanent pacemaker (TPPM) may be an effective and safe alternative. In their article, “A Practical Ambulatory Approach to Atrioventricular Block Secondary to Lyme Carditis,” Aromin and colleagues describe the case of a 31-year-old man who presented

So, how prepared are medical students to properly diagnose patients of all races and ethnicities? Do they have the diagnostic ability and confidence in making a diagnosis, such as Lyme disease, for individuals with non-white skin color? In the study, “The impact of patient skin colour on diagnostic ability and confidence of medical students,” Dodd

Alpha-gal syndrome typically presents with abdominal pain, diarrhea, nausea or vomiting. But it can also lead to swelling of the face or throat, voice changes, difficulty breathing, hives, or fainting, according to recent article “AGA Clinical Practice Update on Alpha-Gal Syndrome for the GI Clinician: Commentary,” by McGill and colleagues.¹ According to the authors, the

In their article “Case report: Subacute transverse myelitis with gait preservation secondary to Lyme disease and a review of the literature,” Colot and colleagues describe a 10-year-old boy who suffered from neck pain with irradiation in the upper limbs for 13 days. Transverse myelitis (TM) is an inflammation of both sides of one section of

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Orbital myositis is typically caused by systemic disease, such as Grave’s disease, or haematological disorders like lymphomas, the authors explain. In these cases, myositis is often bilateral. It has been reported, as well, as a rare manifestation of Lyme disease. In these two cases, myositis was confirmed by MRI findings. Patient #1: 68-year-old female “The

The authors describe a 70-year-old male who presented to the hospital without any typical Lyme disease symptoms, but exhibited generalized symptoms of progressive orthopnea and dyspnea on exertion. The man had a medical history of hypertension and calcific aortic stenosis. His lab results were “significant for an increased erythrocyte sedimentation rate of 136, white blood

In an effort to better understand their significance, Corak and colleagues “grew B. burgdorferi spirochete, round body, bleb, and biofilm-dominated cultures and recovered their transcriptomes by RNAseq profiling.” Their non-spirochete morphotypes were induced by simple changes in growth conditions. The authors described three pleomorphic forms as follows: “Spherical B. burgdorferi cells with intact and flexible