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Lyme Science Blog

Pediatric Lyme Disease Diagnosis Without a Tick Bite

Pediatric Lyme Disease Diagnosed Despite Negative Testing and No Tick Bite A 6-year-old child presented to her pediatrician with a circular rash on the left side of her face. The pediatrician initially suspected allergic dermatitis and prescribed topical steroids. However, the rash failed to improve, explain Banadyha and colleagues in their case report. Over the […]

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Persistent Lyme infection or inflammatory immune response?

Persistent Antigen Lyme Arthritis: What PG(Bb) May Really Mean Persistent antigen Lyme arthritis has gained attention following research suggesting that Borrelia burgdorferi peptidoglycan fragments (PG(Bb)) may drive inflammation even after antibiotic treatment. According to Jutras and colleagues, PG(Bb) fragments likely “contribute to inflammation during infection and in cases of post-infectious Lyme arthritis.” In a mouse

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malaria, mosquito, vector-borne diseases

Stopping the malaria epidemic: lessons for Lyme disease?

Lyme Disease Public Health Failure: Why Tick Control Lags Behind Malaria While there are many differences between disease vectors and the infections they transmit, the authors seek to answer a critical public health question: Why did malaria and other mosquito-borne diseases elicit effective interventions, while Lyme disease and other tick-borne illnesses have not? Lyme disease

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tick, deer tick, powassan virus, tick-borne disease

Ticks: transmitting multiple infectious agents

“Besides the rise in the number of cases of Lyme disease, caused by genospecies of the Borrelia burgdorferi s.l. complex, important tick-borne diseases also include anaplasmosis, ehrlichiosis, Rocky Mountain spotted fever, Powassan virus, and babesiosis,” writes Benelli. [1] Ticks can also be frustrating if your child, livestock, or pet becomes infected. Have you found ticks

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Dismissing chronic Lyme disease for somatic symptom disorder diagnosis

Peri and colleagues reviewed the medical records of children admitted to a hospital in Italy between January 2016 and December 2018. They identified 26 children who had a diagnosis of Lyme disease. Seven fit the criteria for chronic Lyme disease. But the authors disputed these findings, suspecting instead that the patients suffered from a somatic

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dizzy, crowd, dizziness

What exactly is POTS – postural tachycardia syndrome?

POTS: Autonomic Dysfunction, Overlapping Conditions, and Lyme Disease The cause of postural orthostatic tachycardia syndrome (POTS) is not fully understood, but researchers believe it is multifactorial. According to Wells and colleagues, “moderate autonomic dysfunction, increased sympathetic tone, severe deconditioning, inadequate venous return, or excessive venous pooling may contribute to POTS symptoms.” In addition, “autoimmunity and

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fatigue, sleeping, lyme disease

Post-Treatment Lyme Disease Cases Could Reach 2 Million

Post-treatment Lyme disease cases are rising — and a 2019 study estimates nearly 2 million Americans may be affected.For a significant number of patients with Lyme disease, standard antibiotic treatment does not work. In fact, recent studies have shown that treatment failure rates may range between 10% and 20%, writes DeLong and colleagues.These patients can

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Lyme carditis presenting as atrial fibrillation treated successfully

Lyme carditis atrial fibrillation represents an unusual initial presentation that can mislead clinicians. A 23-year-old man’s case demonstrates why atrial fibrillation in young patients from endemic areas deserves immediate Lyme disease consideration — even though classic Lyme carditis typically presents with heart block, not supraventricular arrhythmias. By Dr. Daniel Cameron Initial Presentation: Atrial Fibrillation in

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