Lyme Science Blog

Lyme Science Blog

Lyme Science Blog

Case report: Lyme neuroborreliosis more common in children

“Neurological manifestations are reported in up to 15% of adult patients with Lyme disease, while the frequency among children is higher,” writes Kortela and colleagues from the University of Turku, University of Helsinki and Helsinki University Hospital in Finland. Painful radiculopathy, facial nerve paresis and lymphocytic meningitis are the most common symptoms of neurologic Lyme […]

Lyme Science Blog

Persister cells still a problem for Lyme disease patients

There is increasing evidence of bacterial persistence in microbiology. “Though its applicability to B. burgdorferi has been controversial, persistence is a widely-accepted phenomenon in microbiology which in some instances can have therapeutic implications,” according to Cabello. [1] “While still a matter of dispute, there are numerous reports of antimicrobial treatment unable to completely eliminate B. […]

Lyme Science Blog

Blood donor infects premature infants with Babesia

A team of researchers at Yale School of Medicine describe three premature infants — all in one neonatal intensive care unit — who contracted Babesia from a single 24-year-old blood donor. The report was published in the Pediatric Infectious Diseases Journal. [1] LISTEN TO PODCAST: Three premature babies who contract Babesia from blood transfusions Babesia is a […]

Lyme Science Blog

European Ixodes tick found to carry Alpha Gal protein associated with red meat allergy

Alpha Gal is a sugar molecule that can be spread through the bite of a Lone Star tick. Once bitten, a person’s immune system begins making antibodies to a-Gal. Red meat is rife with it. So most patients become aware of the allergy or illness after they eat red meat. In an interview with National Geographic, […]

Lyme Science Blog

Congenital transmission of babesiosis: two case reports

Congenital transmission has been described in 7 previous cases, in which the infants presented with fever, anemia, and thrombocytopenia, explains Saetre from Cohen Children’s Medical Center in New Hyde Park, New York. “They all required a blood transfusion.” But these are the first cases, to the authors’ knowledge, in which the mother was diagnosed with […]

Lyme Science Blog

Borrelia miyamotoi detected in Canada

To determine the prevalence of the disease, specifically in Manitoba, Canada, Kadkhoda and his team tested randomly selected blood samples from 250 individuals living in that area, who had suspected or confirmed Lyme disease. Samples had been submitted to the Cadham Provincial Laboratory in Manitoba between 2011 and 2014. The authors found that 10% of […]

Lyme Science Blog

High prevalence of Babesia microti in Suffolk County, New York

Ticks were collected in 2015 and 2016 by tick dragging at 5 sites in Suffolk County, New York (Southampton, Mannorville, Southold, Islip, and Huntington) and 3 sites in Connecticut (Mansfield in Tolland County and Stamford and Greenwich in Fairfield County). “As expected, B. burgdorferi (Bb) was the most frequently detected agent in ticks from Suffolk […]

Lyme Science Blog

Could ketamine help manage pain in patients with post-treatment Lyme disease syndrome?

In the International Medical Case Reports Journal, researchers describe a 31-year-old woman with PTLDS “whose pain was refractory to treatment options such as radiofrequency ablation, vitamin infusion therapy, opioid analgesics, and other pharmacotherapies.” [2] Her pain began gradually, 3 years prior and a short time after being diagnosed and treated for Lyme disease, explains Hanna […]

Lyme Science Blog

Doctors agree Lyme disease patients at-risk for suicide are under-recognized group

Bransfield’s colleagues from Howard University, Rush University Medical Center and the University of North Dakota agree with his assessment, stating, “We would like to applaud the author for conducting such an important study by performing a comprehensive assessment of suicide and its association with Lyme-associated diseases (LADs).” [2] In their article “Suicidal and homicidal tendencies […]

Lyme Science Blog

Confirmation of Borrelia burgdorferi in South America

According to investigators, 2 of the 35 Ixodes spp ticks identified tested positive for Bb s.l. [1] The discovery, however, was not unexpected following reports of borreliosis-like disease in Brazil. “During 2009–2016, Brazil registered 4078 suspected cases of borreliosis-like disease, also known as Baggio-Yoshinari syndrome,” states Dall’Agnol from the Instituto de Pesquisas Veterinárias Desidério Finamor […]

Lyme Science Blog

Chronic Lyme disease: Doctors seek answers

Greenberg’s Letter to the Editor states, “The recently published article by Shapiro et al hoped to be topical in this age of ‘alternative facts’ but fell short, providing mainly biased viewpoints that prevent independent assessment of existing research in chronic Lyme disease. Presenting this conclusion as unquestionable is misleading.” [1] Shapiro and colleagues began their […]

Lyme Science Blog

Children in the Netherlands remain ill with post-treatment Lyme borreliosis syndrome

The authors concluded, however, that the symptoms were not due to an active infection, since they lasted longer than 6 months. And therefore, the patients would not benefit from additional rounds of antibiotic treatment.  “As more than 50% of the children had a duration of symptoms of more than 6 months, this further points towards […]

Lyme Science Blog

Transfusion-transmitted babesiosis popping up in more States in USA

Transfusion-transmitted babesiosis (TTB) cases have been reported in Maryland, South Carolina, and Nebraska and “serve as a reminder of the potential for TTB, especially in states not endemic for Babesia,” cautions LeBel II from the Department of Pathology and Laboratory Medicine at the Medical University of South Carolina. In their article published in the journal […]

Lyme Science Blog

Could autonomic dysfunction lead to pain in Lyme disease?

The article, published in Clinical Autonomic Research, cites several cases [2-5] including one in which a 46-year-old patient reports increasing pain and swelling in his left foot. The pain was so significant that his leg became dysfunctional, according to the authors. “Even the slightest contact with the skin of the affected area caused the patient unbearable pain.” [2] […]

Lyme Science Blog

Suicidal behaviors in patients with Lyme and associated diseases

by Daniel J. Cameron, MD MPH In a 1990 report, Logigian and colleagues from Tufts University School of Medicine, Boston, describe rage in patients with chronic neurologic Lyme disease. “Eight patients had excessive daytime sleepiness, and seven had extreme irritability. They became angry over circumstances that previously caused only minor annoyance.” [1] In 1994, Fallon […]