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Dr. Daniel Cameron

Board-certified physician with 38+ years specializing in Lyme disease and tick-borne illnesses. Past President of ILADS (International Lyme and Associated Diseases Society) and first author of ILADS treatment guidelines. Dr. Cameron operates a solo practice focused on patient advocacy and evidence-based Lyme disease treatment. He is the author of 1,100+ articles spanning diagnosis, treatment, co-infections, and recovery from tick-borne illnesses. His work challenges conventional approaches that often leave patients undiagnosed or undertreated, emphasizing clinical judgment over rigid adherence to testing criteria that frequently produce false negatives.

Dr. Daniel Cameron

Seizures and altered mental status after a tick bite

Seizures after tick bite signal a medical emergency requiring immediate investigation for tick-borne infection. A 66-year-old woman reported removing a tick two weeks before admission, then developed fever, fatigue, rash, and altered mental status — yet tick-borne disease wasn’t considered until she had generalized tonic-clonic seizures 38 hours into hospitalization. Her diagnosis was human monocytic […]

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Fatigue can be overlooked as a “sign” of Lyme disease

Fatigue is one of the most common symptoms of Lyme disease — yet it is frequently overlooked, underestimated, or attributed to other causes. Research shows fatigue is present across every stage of Lyme disease, from early infection to chronic neurologic involvement, and may be one of the most important signals that infection has not resolved.

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PTLDS symptoms

How can doctors determine if patients with systemic autoimmune joint disease following Lyme disease don’t have a persistent infection?

by Daniel J. Cameron, MD MPH The patients were prescribed anti-inflammatory therapies, primarily disease-modifying anti-rheumatic drugs (DMARDs). “These treatments included steroids (3%), NSAIDS (20%), disease-modifying anti-rheumatic drugs (DMARDs) (57%), most commonly methotrexate, but also TNF-inhibitors, or combinations of these agents,” reported Arvikar. [1] The authors assumed that the persistent Borrelia burgdorferi (Bb) infection had been

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Quality of Life for Lyme Disease patients in the Netherlands can be grim

by Daniel J. Cameron, MD MPH Participants in the PLEASE trial were scored using an SF-36 physical component of Health (PCS) scale. Their PCS scores of 31 to 32 were worse than those of a diabetic and cancer patient. [3] These patients’ PCS scores have been 42 and 41, respectively. While PCS scores have been

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Steroid use can lead to long-term treatment failure for Lyme disease patients

Physicians are warned of the importance in distinguishing between viral or idiopathic facial paralysis (e.g., Bell’s palsy) from Lyme disease-associated facial palsy. Authors of the study, “Steroid Use in Lyme Disease-Associated Facial Palsy Is Associated With Worse Long-Term Outcomes,” used the term Lyme disease-associated facial palsy (LDFP) rather than Bell’s palsy to highlight the differences

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Women with chronic Lyme disease may suffer from a severe immune response triggered by the disease

According to a study by Wormser and colleagues, from New York Medical College, “Patients with chronic Lyme disease were significantly more likely to be female than were patients diagnosed with either Lyme disease or with post-Lyme disease syndrome.” “This finding,” says Wormser, “suggests that illnesses with a female preponderance, such as fibromyalgia, chronic fatigue syndrome,

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How big is the risk of Lyme disease to your job?

by Daniel J. Cameron, MD MPH Doctors from the Tufts University School of Medicine, New England Medical Center described the financial damage Lyme disease caused to 27 individuals with chronic neurologic Lyme disease. “Although most were able to remain employed, three quit their jobs, three decreased their work load to part-time, and two retired earlier,”

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How important are T-cell chemokines in chronic manifestations of Lyme disease?

The study, “CCL19 as a Chemokine Risk Factor for Post-Treatment Lyme Disease Syndrome: A Prospective Clinical Cohort Study,” found T-cell chemokines are an important part of the immune response in early Lyme disease (LD). Researchers at Johns Hopkins identified T-cell chemokines CCL19 that rise in early LD then drop to normal in 86% of patients

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Watch and wait approach does not work for Lyme disease

by Daniel J. Cameron, MD MPH Physicians who prescribe no more than a three-week course of antibiotics will typically recommend watchful waiting rather than prescribing additional antibiotic treatment for patients suffering with persistent symptoms. However, two leading research groups have described the dangers in not taking action. Investigators at Johns Hopkins University School of Medicine

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