Lyme Science Blog

Nanotrap Lyme Test: Early Research Into Urine Detection The Nanotrap Lyme test uses urine-based antigen detection. Researchers explored whether OspA proteins could improve Lyme disease detection. The technology gained attention because of broader infectious disease applications. Ceres Nanosciences marketed the Nanotrap® Lyme test as a urine-based antigen detection tool designed to identify Borrelia burgdorferi proteins […]

Can Lyme Disease Affect the Kidneys? Minimal Change Disease Case Report Lyme disease and kidney disease associations are rare, but isolated case reports suggest Lyme disease may contribute to certain immune-mediated kidney disorders. Lyme disease is primarily associated with neurologic, cardiac, and musculoskeletal symptoms, though less common organ involvement has also been described. One case

Tick Bite Risk at Outdoor Events: Study Findings Outdoor events may increase exposure to ticks, particularly in endemic areas. A study of long-distance mountain racers in Scotland highlights the frequency of tick bites during multi-day outdoor activities. This raises an important question: how common are tick bites during outdoor events? Findings suggest that exposure may

Is Lyme Disease a Hoax? Patients frequently ask whether Lyme disease is real, whether chronic Lyme disease is a hoax, or whether persistent symptoms after treatment are “fake.” These questions reflect a decades-long debate involving terminology, testing limitations, persistent symptoms, and disagreements over treatment approaches. Lyme disease itself is not controversial. It is a recognized

Relapsing Fever vs Lyme Disease: Borrelia miyamotoi Symptoms Relapsing fever symptoms can overlap with Lyme disease Borrelia miyamotoi may not cause classic recurrent fevers Testing limitations can complicate diagnosis Relapsing fever vs Lyme disease can be difficult to distinguish because patients with Borrelia miyamotoi often present with symptoms that overlap with Lyme disease and other

Lyme Disease in a Traveler: Diagnosis in an American Patient Abroad Lyme disease can be missed when patients present outside endemic regions. Travel history and erythema migrans helped confirm the diagnosis. This case highlights diagnostic challenges for clinicians abroad. Lyme disease can present in travelers outside endemic regions, creating diagnostic challenges for clinicians unfamiliar with

Borrelia Miyamotoi in Travelers: Imported Case with Lyme Coinfection Borrelia miyamotoi is an emerging tick-borne infection that may affect travelers returning from endemic regions. A case from Japan highlights the risk of infection after exposure in the United States. This raises an important question: should Borrelia miyamotoi be considered in travelers with fever after tick

Lyme Disease Vaccine Efficacy: Questions from the OspA Trial The Lyme disease OspA vaccine demonstrated effectiveness in preventing certain early manifestations, but important questions remain regarding its overall efficacy. This raises an important question: how effective was the Lyme disease vaccine across different clinical outcomes? Trial data suggest strong protection against confirmed erythema migrans, but

Neurologic Lyme Disease: Immune Markers Linked to Persistent Symptoms Some patients with neurologic Lyme disease remain symptomatic after treatment, raising important questions about underlying mechanisms. Research suggests that immune system activity in the central nervous system may play a role in recovery. This raises an important question: what is happening in the brain of patients

Lyme Carditis Case Without Heart Block: Missed Early Signs Lyme carditis is often associated with heart block, but cardiac involvement can present in other ways. A case from Cape Cod highlights how Lyme disease may affect the heart even without classic conduction abnormalities. This raises an important question: can Lyme carditis present without heart block?