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Lyme Science Blog

6-year-old girl with a rare cutaneous presentation of Lyme disease

The 6-year-old girl presented with an erythema migrans (EM) rash before developing an areolar lymphocytoma involving her breast. She had recently travelled to Germany, where her parents recalled her developing an asymptomatic, annular, erythematous eruption of the right flank 1 week after a “bite,” writes Ogimi. The initial tests for Lyme disease were negative. Then, […]

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Study shows doctors can misdiagnose Lyme disease

The study included more than 1,000 children, average age of 9, who underwent evaluation for Lyme disease at 1 of the 5 participating emergency departments. The authors found that 65 out of 554 children (12%) could have been underdiagnosed. “Of the 554 children who the treating clinicians thought were unlikely to have Lyme disease (score

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Single dose of doxycycline for Lyme disease led to poor outcome for 61-year-old man

In the January 2018 issue of the British Medical Journal, the authors describe the case of a 61-year-old man who complained to his primary care physician and multiple emergency room personnel that he was having severe shooting pain over his scalp, neck and back. “The degree of discomfort from his hair moving was so extreme

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Ticks and Lyme disease bacteria with us since the Ice Age

In an effort to explore the evolutionary history of the spirochete B. burgdorferi in North America, Walter and colleagues from the Department of Epidemiology of Microbial Disease at Yale University collected ticks from across the USA and southern Canada between 1984 and 2013. The authors sequenced what they believe to be the largest collection of 146

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Lyme patient fails to seek treatment until illness renders him unconscious

The 66-year-old man became ill within a week of being bitten by a tick on the back of his neck. One month later, he collapsed and was rendered unconscious, Sharma and colleagues explain in The American Journal of Medicine. The authors describe the case in their article “Without Further Delay: Lyme carditis.” When the man was

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Tracking ticks in West Virginia using man’s best friend

Researchers have conducted numerous animal sentinel studies to monitor the occurrence and spread of Lyme disease. “These studies primarily focused on ticks and associated pathogens collected from domestic dogs because of their ability to produce antibodies to B. burgdorferi, attainable travel history information, and frequency of outdoor exposure,” says Hendricks. Hendricks’ team looked at confirmed

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Borrelia spirochete are masters at evading immune system

Mice, guinea pigs, dogs, rabbits and monkeys have long been used to study B. burgdorferi infections. But given that rhesus macaques have been shown to most accurately mimic human infection and response to treatment, Embers and her team inoculated rhesus macaques with B. burgdorferi. “The use of nonhuman primates to model this disease provides the

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Case report: Persistent pain and fatigue after treatment for Lyme disease

The patient was concerned she might have Lyme disease because she had repeated exposure to ticks and had reported tick bites in the past. However, “She did not recall a tick bite in the weeks preceding the onset of her illness,” Novak writes in Case Reports in Infectious Diseases. [1] Therefore, the primary care doctor made

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40 years after first case, Lyme disease still a burden for Connecticut

Since 1977, “in spite of all endeavors conducted by the Connecticut Department of Public Health (CTDPH) to control the disease, it [Lyme disease] remains endemic with substantial morbidity rates,” states Mollalo, from the Department of Geography at the University of Florida. Mollalo and his team conducted a retrospective study examining changes in the spatial clusters

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