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Sick for years with Post-Treatment Lyme Disease Syndrome

Video Blog: Sick for years with Post-Treatment Lyme Disease Syndrome

by Daniel J. Cameron, MD MPH The study focuses on the similarities and differences in male and female Lyme disease patients. However, the authors give little attention to the fact that both the male and female participants suffered from Post-Treatment Lyme Disease Syndrome a decade after treatment. A growing number of studies describe individuals sick […]

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problems with 2-week course of antibiotics for Lyme disease

Video Blog: More problems with 2-week course of antibiotics for Lyme disease

by Daniel J. Cameron, MD MPH As early as 1990, Logigian and colleagues hypothesized that a two-week course of intravenous ceftriaxone would not successfully eradicate the Lyme bacterium. “The likely reason for relapse is failure to eradicate the spirochete completely with a two-week course of intravenous ceftriaxone therapy.” [3] A recently published clinical trial from

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Reversible causes of Dementia

Reversible causes of Dementia and Normal Pressure Hydrocephalus

According to Rolling Stone, doctors believed the 79-year-old singer’s “increasingly debilitating memory loss was due to either Alzheimer’s or to dementia brought on by blows to the head from the boxing, football and rugby of his teens and early twenties.” He reportedly could not remember what he was doing from one moment to the next,

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LADS Lyme disease guidelines rank in top 5% of all research articles

ILADS Lyme disease guidelines rank in top 5% of all research articles, as scored by Altmetrics

by Daniel J. Cameron, MD MPH Altmetrics are metrics and qualitative data that are complementary to traditional, citation-based metrics that track and demonstrate the reach and influence of research publications to key stakeholders. [1] The Altmetrics score “can signal that research is changing a field of study, the public’s health, or having any other number of

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Lyme disease Netherlands clinical trial

Video Blog: Netherlands trial does not support short-term therapy for Lyme disease

by Daniel J. Cameron, MD MPH In the article, Randomized Trial of Longer-term Antibiotic Therapy for Symptoms Attributed to Lyme Disease, the authors “assessed whether longer-term antibiotic treatment of persistent symptoms attributed to Lyme disease leads to better outcomes than does shorter-term treatment.” They report that “longer-term antibiotic treatment did not have additional beneficial effects

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JAMA review ignores chronic manifestations of Lyme disease

JAMA review ignores chronic manifestations of Lyme disease

by Daniel J. Cameron, MD MPH “Multiple trials have shown efficacy for a 10-day course of oral doxycycline for treatment of erythema migrans and for a 14-day course for treatment of early neurologic Lyme disease in ambulatory patients,” the review concludes. Furthermore, “Evidence indicates that a 10-day course of oral doxycycline is effective for HGA

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Retraction: Still no evidence that deer flies or deer keds transmit B. burgdorferi or A. phagocytophilum

by Daniel J. Cameron, MD MPH The Journal of Vector Ecology was talking about deer keds seen below (family Hippoboscidae, genus Lipoptena), not deer flies (family Tabanidae, genus Chrysops). Thomas Mather pointed out a fun blog about this “tick with wings” at https://www.tickencounter.org/tick_notes/tick_notes_deer_keds#top 2. The Anaplasma phagocytophilum identified in the paper has not been identified

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Don’t dismiss the poor quality of life for individuals with Lyme disease

Don’t dismiss the poor quality of life for individuals with Lyme disease

by Daniel J. Cameron, MD MPH In the recent Clinical Infectious Diseases article entitled “Long-term follow-up of patients with Lyme disease: Longitudinal analysis of clinical and quality of life measures,” the authors conclude that “both mental health and physical health scores increased to be at or above national average over time, regardless of Lyme disease

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Tick-borne co-infections are the norm, not the exception

Tick-borne co-infections are the norm, not the exception

Lyme disease was first identified in 1975 in a group of children and adolescents living in Connecticut, who suffered from recurrent attacks of asymmetric swelling and pain in several large joints, particularly in the knee. The patients were initially diagnosed with juvenile rheumatoid arthritis. “The typical patient has had 3 recurrences, but 16 patients have

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What might sudden cardiac death due to Lyme disease look like?

What might sudden cardiac death due to Lyme disease look like?

by Daniel J. Cameron, MD MPH Fatal Lyme carditis is rarely identified. In reviewing five post mortem cases, Muehlenbach and colleagues found that Lyme disease was not suspected for one patient who complained of episodic shortness of breath, while the second patient tested negative for Lyme disease. Two other patients did not seek medical care.

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