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Lyme Science Blog

Autonomic dysfunction, small fiber neuropathy and Lyme disease

A retrospective study of 10 patients diagnosed with post-treatment Lyme disease syndrome found that all had small fiber neuropathy, autonomic dysfunction, and abnormal cerebral blood flow — providing objective evidence for symptoms that are often dismissed. The findings suggest that small fiber neuropathy may be a measurable biomarker of persistent Lyme disease symptoms, particularly in […]

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Where are the ticks and what are the diseases they carry?

Northern ‘immigrant’ ticks causing concern in the South

“While questing, ticks hold onto leaves and grass by their third and fourth pair of legs. They hold the first pair of legs outstretched, waiting to climb onto the host,” according to researchers from the Centers for Disease Control and Prevention (CDC). “When a host brushes the spot where a tick is waiting, it quickly

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antibiotics, pills, medication

Failure rates still too high for treatment of Lyme disease

According to the authors, the 14-day course effectively cleared the patients’ erythema migrans rashes and “prevented the development of objective neurologic, cardiac, or rheumatologic manifestations.” One patient was retreated with amoxicillin. Two others could not be evaluated at 1-year follow-up due to a recurrent erythema migrans (EM) rash. But 4 out of the 24 patients

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doctors reviewing x-rays

Lyme-like syndrome in Brazil is still a problem

Brazilian Lyme-like syndrome (BYS) is a tick-borne illness that closely resembles Lyme disease. Recent polymerase chain reaction (PCR) testing has confirmed the presence of Borrelia burgdorferi sensu stricto in Brazil, strengthening evidence that this condition represents a true borrelial infection rather than a distinct or unrelated syndrome. The existence of Borrelia burgdorferi s.s. in Brazil

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Headaches in Lyme disease patient with acute transverse myelitis

Acute transverse myelitis in a 25-year-old man with Lyme disease

Acute transverse myelitis is a rare neurologic condition that leaves one-third of patients with severe neurologic disability. It is characterized by varying degrees of bilateral motor, sensory, and autonomic dysfunction. Symptoms can progress rapidly within hours or within days, explains Dumic, from Mayo Clinic and lead author of the case report “Acute transverse myelitis: A

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veterans with lyme disease

USA veterans suffer from tick-borne illnesses

Lyme Disease Veterans: Symptoms, Co-Infections, and Missed Diagnoses In a study examining Lyme disease veterans receiving care through the Veterans Affairs system, investigators reviewed clinical and laboratory findings to better understand the presentation of Lyme disease and related tick-borne infections. The authors found that out of 181 veterans evaluated, 32 presented with an erythema migrans

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back pain, Lyme disease

Lyme Myelopathy: Acute Transverse Myelitis as a Treatable Cause

Lyme Myelopathy: Acute Transverse Myelitis as a Rare but Treatable Complication Clinical signs and symptoms of acute transverse myelitis (ATM) depend on the region of the spinal cord involved, explain Kaiser and colleagues in a recent case report, “Lyme myelopathy: Case report and literature review of a rare but treatable disorder.” The causes of acute

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diagnosing Borrelia miyamotoi

Diagnosing Borrelia Miyamotoi: Blood Smear Not Reliable

Diagnosing Borrelia miyamotoi can be challenging. Some doctors have suggested that a blood smear should be used to confirm the diagnosis of BMD. But as Telford and colleagues demonstrate, a blood smear may not be so reliable for diagnosing Borrelia miyamotoi. [1] In an effort to determine whether blood smears can detect B. miyamotoi in

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eyes, eye, vision

Erratic rapid eye jerks in a child with Lyme disease

Opsoclonus is typically due to an infectious disease or a form of cancer, known as neuroblastoma. In some cases, the cause is unknown. But the condition is rarely seen in Lyme disease patients, explains Gibaud and colleagues in the case report “Opsoclonus in a child with neuroborreliosis.” [1] In fact, only 2 cases have been

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depression, anxiety

Depression Scores in Lyme Disease May Reflect Physical Symptoms

A one-year prospective study followed 52 adult Lyme disease patients who presented with erythema migrans (EM) rashes. Participants reported a range of somatic symptoms, including fatigue, headaches, joint pain, muscle pain, and cognitive complaints. Patients with more severe physical symptoms also had higher scores on the Beck Depression Inventory–II (BDI-II). The BDI-II is commonly used

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