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Study identifies189 children with Lyme carditis
In reviewing medical records from a Pediatric Health Information System (PHIS) database between 2007 and 2013, clinicians identified 189 children diagnosed with Lyme carditis. “The burden of Lyme disease and Lyme carditis in U.S. children’s hospitals has increased in recent years,” writes Beach and colleagues in Pediatric Cardiology.
Brain MRI in Lyme disease
Infectious pathogens, including viral, bacterial and parasitic, can impact the central nervous system (CNS), resulting in neurologic disease. “The infections caused by these pathogens often show a variety of neuroimaging patterns that can be identified [on a] CT scan and MRI,” explains Alves Simão and colleagues. ¹ Radiology, they argue, is central to the diagnosis and follow-up of these conditions. Therefore, “radiologists should be familiar with these infections.”
C6 peptide test may indicate Borrelia miyamotoi infection
The C6 enzyme immunoassay (EIA) is often used to diagnose Lyme disease. The test is based on the C6 peptide of the Borrelia burgdorferi sl VlsE protein. But a recent study suggests the C6 peptide test may also indicate an infection with Borrelia miyamotoi, another tick-borne disease.
Treatment of Lyme arthritis with disease-modifying antirheumatic drugs (DMARD)
Editorial: I am concerned with the subgroup of Lyme arthritis (LA) patients described by Dr. Steere, who “developed a marked inflammatory, proliferative synovitis lasting months to several years after antibiotic treatment.”
Could advanced imaging reveal cognitive impairment in the brain of a Lyme disease patients?
Clinicians can now measure neurotransmitter levels in the brains of patients with mild cognitive impairment using magnetic resonance spectroscopy (MRS) with advanced 7 Tesla technology. MRS, also referred to as Nuclear Magnetic Resonance (NMR), shows the “levels of gamma-aminobutyric acid (GABA), glutathione and other neurotransmitters in brain regions of interest with greater precision than previous, lower-strength imaging systems,” explains Oeltzschner and colleagues. ¹
Consequences of antibiotic stewardship for Lyme disease patients. An opinion.
Could antibiotic stewardship lead to delayed treatment for Lyme disease? In a recent article, researchers in England describe the potential consequences of antibiotic stewardship in an elderly population with urinary tract infections (UTI).
My child has Lyme disease. Parents describe fear and frustration.
At least 25% of all reported Lyme disease cases in the United States involve children under age 14, according to the Centers for Disease Control and Prevention (CDC). Children and adolescents are among the most at-risk group for developing Lyme disease. Yet, their symptoms often go unrecognized or are dismissed, enabling the disease to progress.
How many patients do not meet the CDC criteria for Lyme disease?
In a recent article published in Open Forum Infectious Disease, Kobayashi and colleagues suggest that Lyme disease is often mistakenly diagnosed as causing various illnesses, which has led to the unnecessary use of antibiotics. The authors conducted a retrospective study of patients with possible Lyme disease, who were referred to an infectious disease clinic in Maryland between 2000 and 2013. ¹
Hispanic risk of Lyme disease.
Outdoor workers are at a greater risk of getting a tick bite than the general population. In fact, their risk is more than 5 times greater, explains Hu in the journal Zoonoses Public Health. Many of those outdoor workers are Hispanic, who represent “44.8% of grounds maintenance workers and 42.8% of workers in the farming, fishing and forestry industries,” Hu writes, citing U.S. Department of Labor Statistics from 2018.
Lyme vaccine for humans. The race for a new vaccine.
It has been nearly two decades since the Lyme disease vaccine LYMErix was pulled off the market by its manufacturer, SmithKline Beecham. The vaccine was designed to prevent the transmission of the tick-borne bacterial agent Borrelia burgdorferi, which causes Lyme disease.
