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Azithromycin gel fails to prevent Lyme disease

In a recent study conducted in Germany and Austria, researchers applied a 10% azithromycin gel to the site of a tick bite for 3 days. The trial was stopped early after it failed to prove that the gel worked in preventing Lyme disease (LD) for the 995 subjects. The topical treatment failed to prevent a combination of seroconversion or an EM rash in 11 (2%) of 505 individuals in the azithromycin group and 11 (2%) of 490 participants in the placebo group.

Borrelia burgdorferi infected deer ticks in the Outer Banks of North Carolina

A recent study on the transmission of Borrelia burgdorferi (Bb), the spirochete associated with Lyme disease, in the Outer Banks of North Carolina (NC), highlights the difficulties in determining the actual risk of Bb-infected ticks present in particular regions. [1]

All Things Lyme – top 15 blogs for 2016

As another year comes to a close, we share with you the most popular blogs for 2016 from our All Things Lyme blog series. Throughout the year, dozens of studies, published in leading scientific journals, continued to demonstrate the potential seriousness of Lyme disease and other tick-borne diseases when left untreated or improperly treated. The ramifications for patients can be life-altering.

Further evidence of Borrelia burgdorferi sensu stricto associated with Lyme disease in the South

Much attention has been given to the Southern Tick-Associated Rash Illness (STARI), transmitted by the Lone Star tick (Amblyomma americanum) in the South. [1] However, a new study reminds us that the causative agent of Lyme disease, Borrelia burgdorferi sensu stricto has been in the South since at least 1991. [2]

Eye problems in tick-borne diseases other than Lyme

“Why should an ophthalmologist have a good understanding of Lyme diagnosis and treatment?” asks Sathiamoorthi [1], from the Mayo Clinic, in an article published in the Current Opinion in Ophthalmology. “Vision-threatening ophthalmic manifestations are relatively common in Lyme disease (LD) and Rocky Mountain spotted fever.”

Study raises concerns for Babesia patients and blood banks

Babesiosis, an emerging tick-borne disease caused by the parasite Babesia microti, is currently the highest ranked pathogen transmitted by blood transfusions. The infection can go undetected as healthy individuals may be asymptomatic or symptoms are subtle. But for others, it can cause chronic, debilitating illness.

Lyme meningitis, manifesting as Parkinsonism, is fully reversed with ceftriaxone

An abstract published in Critical Care Medicine discusses what the authors believe is the first reported case of Lyme meningitis “presenting with symptoms suggestive of rapidly progressing Parkinsonism.” The case report describes a patient whose symptoms resolved when proper treatment was initiated.

Hair loss in Lyme disease – the last straw?

We thought we had enough problems with the discovery of chronic Lyme disease, Lyme encephalopathy, and neuropsychiatric Lyme disease. [1] Hair loss could be the last straw.

Needless criticism for doctors treating Lyme disease

Lyme disease (LD), an illness that can be extremely difficult to diagnose and treat, is made even more challenging when physicians criticize one another about managing such complex cases. The authors of a recent report published in JAMA Internal Medicine took aim at doctors who diagnose and treat Lyme disease. [1]

Can we measure the brain’s exaggerated response to pain and sensory input?

A team of researchers in Colorado have demonstrated the effectiveness of utilizing neuroimaging-based tools to help validate pain symptoms and gauge treatment response in patients with fibromyalgia (FM). Such techniques have the potential to benefit Lyme disease patients by helping to determine the effectiveness of various therapies for each patient.