Lyme Disease in Texas and the Southern United States Blacklegged ticks have been identified in Texas. Researchers continue to study Lyme disease in the South. Tick-borne illnesses may be underrecognized in southern states. Lyme disease has traditionally been associated with the Northeast and Upper Midwest. However, investigators continue to report evidence of tick-borne illnesses in […]
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Lyme Disease Treatment Cost and Economic Impact Lyme disease can create major financial burdens for patients and society. Costs rise significantly for patients with chronic manifestations or PTLDS. Productivity losses account for a large portion of the economic impact. Lyme disease treatment cost can be substantial, particularly for patients with chronic manifestations or Post-Treatment Lyme
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Is Lyme Disease New? What History Reveals About an Ancient Infection Is Lyme disease new? Although Lyme disease was first recognized in Connecticut in the 1970s, evidence suggests the bacteria responsible for the illness have existed for thousands — and possibly millions — of years. Lyme disease is not a newly created illness—it is an
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Positive IgM Immunoblot in Children With Lyme Disease Researchers examined positive IgM immunoblots in children. Some positive results were questioned as false positives. Clinical judgment remains essential in pediatric Lyme disease. Lantos and colleagues from Duke University Medical Center questioned the accuracy of the IgM immunoblot for Lyme disease in children and adolescents by reviewing
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Novel Drug Combinations for Lyme Persister Cells: What Researchers Found Laboratory studies identified drugs active against Lyme persister cells Round body forms may respond differently to antibiotics Clinical relevance remains uncertain In a study entitled A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA
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Post-Treatment Lyme Disease Syndrome: Why Some Patients Remain Ill for Years Post-Treatment Lyme Disease Syndrome (PTLDS) describes patients who continue to experience symptoms months or even years after treatment. A growing body of research highlights the long-term impact of Lyme disease in a subset of individuals. :contentReference[oaicite:0]{index=0} Persistent Symptoms Are Well Documented Several studies have
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Do Short Courses of Antibiotics Fall Short in Lyme Disease? Standard treatment for Lyme disease often includes a 2–3 week course of antibiotics. However, several studies have raised questions about whether this duration is sufficient for all patients. :contentReference[oaicite:0]{index=0} Early Concerns About Treatment Duration As early as 1990, Logigian and colleagues suggested that a two-week
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Can Lyme Disease Mimic Dementia? When Cognitive Decline May Be Reversible Can Lyme disease mimic dementia? Yes. Lyme disease can cause memory loss, confusion, and cognitive decline that may resemble dementia — and in some cases, these symptoms may improve with treatment. Unlike Alzheimer’s disease or other neurodegenerative conditions, Lyme-related cognitive symptoms may be driven
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Why ILADS Lyme Disease Guidelines Drew Widespread Attention Persistent symptoms shaped the guidelines GRADE methodology informed recommendations Patient outcomes remain the key question The ILADS Lyme disease guidelines attracted attention beyond traditional academic citations because they addressed persistent symptoms, treatment uncertainty, and controversial aspects of Lyme disease management. Research impact is often measured through citation
Netherlands Trial: Does It Really Support Short-Term Lyme Disease Therapy? A randomized trial published in the New England Journal of Medicine evaluated whether longer-term antibiotic treatment improves outcomes in patients with persistent symptoms attributed to Lyme disease. :contentReference[oaicite:0]{index=0} The authors concluded that longer-term therapy did not provide additional benefit compared to shorter-term treatment. Who Was
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